Based on the aggregated intelligence of 180,000-plus investors participating in Motley Fool CAPS, the Fool's free investing community, biopharmaceutical company Orexigen Therapeutics (Nasdaq: OREX) has received the dreaded one-star ranking.

With that in mind, let's take a closer look at Orexigen's business and see what CAPS investors are saying about the stock right now.

Orexigen facts

Headquarters (founded) La Jolla, Calif. (since 2002)
Market Cap $399.9 million
Industry Biotechnology
Trailing-12-Month Revenue $3.4 million
Management CEO Michael Narachi (since 2009)
Acting CFO Joseph Hagan (since 2011)
Return on Capital (average, past 3 years) (51.4%)
Cash/Debt $138.6 million / $0
Competitors Abbott Labs
Arena Pharmaceuticals
(Nasdaq: ARNA)
GlaxoSmithKline

Sources: S&P Capital IQ and Motley Fool CAPS.

On CAPS, 24% of the 262 All-Star members who have rated Orexigen believe the stock will underperform the S&P 500 going forward.

Just yesterday, one of those bears, jed71, cautioned Fools about getting too excited over Orexigen's recent speculation-fueled surge:

Obesity drug still not approved yet. Run up based on expectations and approval received by a different company, Arena Pharma, for a similar obesity drug. It will not hold the run up, because, well, [Orexigen] never holds these run ups.

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