Track the companies that matter to you. It's FREE! Click one of these fan favorites to get started: Apple; Google; Ford.



3 Possible Catalysts for Inovio Pharmaceuticals in 2014

Don't let it get away!

Keep track of the stocks that matter to you.

Help yourself with the Fool's FREE and easy new watchlist service today.

There's a real buzz around Inovio Pharmaceuticals (NASDAQ: INO  ) .

Indeed, shares have have risen from $0.72 one year ago to $2.82 at the time of writing. That's a gain of 291%. I don't need to tell you that the major U.S. indices posted gains that were only fractions of that amount over the same period.

Moreover, much of that gain has come the last eight months or so, and the buzz surrounding Inovio Pharmaceuticals culminated in the company being invited by the New York Stock Exchange to ring the opening bell on Feb. 12.

Much of the hype surrounding Inovio has to do with the future -- more specifically, the potential catalysts for the stock. Here are three that could be worth keeping an eye on throughout 2014 (this list is not exhaustive).

1. The exclusive worldwide partnership with Roche to develop and commercialize products from Inovio Pharmaceuticals' prostate cancer and hepatitis B immunotherapy programs appears to be making encouraging progress. Although Inovio remains tight-lipped about the identity of other large pharmaceutical companies with whom it is in discussions, those discussions are ongoing and further news is likely to surface during the year.

2. Although Inovio manages a relatively broad portfolio of immunotherapies, its lead program remains focused on cancer immunotherapy. Efficacy data from the phase 2 trial of this program is due to be released in the second or third quarter of this year and could have a major impact on the stock price.

3. Inovio expects to update the market throughout the year on both its prostate cancer and hepatitis B therapies with Roche, but also initiate several new clinical trials for cancer immunotherapies. Updates from these trials could impact the stock price, too.

Of course, Inovio Pharmaceuticals isn't the only stock garnering some buzz in 2014. Other health care companies that are focused on immunotherapies have also seen their share prices deliver notable movements, with two obvious examples being ImmunoCellular Therapeutics (NYSEMKT: IMUC  ) and Galena Biopharma (NASDAQ: GALE  ) .

ImmunoCellular Therapeutics has seen its share price move from roughly $0.92 at the start of the year to $1.21 as of the closing bell Wednesday, although it should be noted that it reached as high as $1.56 before pulling back. As with Inovio, the company has numerous potential catalysts for the year ahead, including a meeting with the FDA to discuss phase 2 results for its lead product candidate, the brain cancer treatment ICT-107, as well as a decision from the European Medicines Agency on whether ICT-107 will be granted an orphan designation.

Meanwhile, Galena Biopharma's share price is at the same level as it was on New Year's Eve. However, this doesn't tell the whole story because the stock has been as much as 50% higher as a result of the company's deal to purchase Mills Pharmaceuticals for $200 million, a strategic partnership for breast cancer drug NeuVax in India, and positive updates surrounding a phase 2 trial for cancer immunotherapy GALE-301.

It could be worth keeping an eye on all three immunotherapy-focused companies. With the buzz surrounding its current share price and the three catalysts mentioned above, 2014 could be a very interesting year for Inovio Pharmaceuticals in particular.

The Motley Fool's Top Stock For 2014

There's a huge difference between a good stock and a stock that can make you rich. The Motley Fool's chief investment officer has selected his No. 1 stock for 2014, and it's one of those stocks that could make you rich. You can find out which stock it is in the special free report "The Motley Fool's Top Stock for 2014." Just click here to access the report and find out the name of this under-the-radar company.

Read/Post Comments (1) | Recommend This Article (0)

Comments from our Foolish Readers

Help us keep this a respectfully Foolish area! This is a place for our readers to discuss, debate, and learn more about the Foolish investing topic you read about above. Help us keep it clean and safe. If you believe a comment is abusive or otherwise violates our Fool's Rules, please report it via the Report this Comment Report this Comment icon found on every comment.

  • Report this Comment On February 13, 2014, at 12:11 AM, theNextThing wrote:

    In my opinion,

    if investors recognized what “dosage” was used for all of its study subjects in its lead program in Phase 2 (VGX-3100 Cervical Dysplasia) & what kind of efficacy it achieved in Phase 1, they can have a good idea of its probability of delivering positive result in mid-2014.

    Find out for yourselves & make your own assessments :

    - Watch this video (from 9:30 - 11:00)

    - Phase I Study Protocol for VGX-3100

    (Look for three doses tested)

    - Phase II description :

    Read “Clinical Trials” section (Look for a dosage used)

    & “Study Data” section (Review T-cell Response Chart)

Add your comment.

Sponsored Links

Leaked: Apple's Next Smart Device
(Warning, it may shock you)
The secret is out... experts are predicting 458 million of these types of devices will be sold per year. 1 hyper-growth company stands to rake in maximum profit - and it's NOT Apple. Show me Apple's new smart gizmo!

DocumentId: 2837042, ~/Articles/ArticleHandler.aspx, 8/31/2015 2:11:09 PM

Report This Comment

Use this area to report a comment that you believe is in violation of the community guidelines. Our team will review the entry and take any appropriate action.

Sending report...

Today's Market

updated Moments ago Sponsored by:
DOW 16,551.24 -91.77 -0.55%
S&P 500 1,977.48 -11.39 -0.57%
NASD 4,800.03 -28.29 -0.59%

Create My Watchlist

Go to My Watchlist

You don't seem to be following any stocks yet!

Better investing starts with a watchlist. Now you can create a personalized watchlist and get immediate access to the personalized information you need to make successful investing decisions.

Data delayed up to 5 minutes

Related Tickers

8/31/2015 1:54 PM
GALE $1.57 Up +0.07 +4.67%
Galena Biopharma,… CAPS Rating: *
IMUC $0.43 Up +0.02 +4.88%
ImmunoCellular The… CAPS Rating: *
INO $7.58 Down -0.15 -1.94%
Inovio Pharmaceuti… CAPS Rating: ***