Rumors have been swirling lately that Walgreen (NASDAQ:WBA) will attempt to move early on its option to purchase the remaining 55% of British retail pharmacy Alliance Boots (it already owns 45% of the company). While it doesn't look particularly likely that Walgreen will actually move early, the contract it has with Boots stipulates that Walgreen could go ahead with the massive transaction starting next February.

So, the #1 question investors should ask about this potential acquisition is obvious: Would the combination make sense? 

In the video below, from Market Checkup, the Motley Fool's health care-focused investing show, health care analysts Michael Douglass and David Williamson lay out the potential synergies between Walgreen and Alliance Boots and their take on the potential deal.

David Williamson has no position in any stocks mentioned. Michael Douglass has no position in any stocks mentioned. The Motley Fool has no position in any of the stocks mentioned. Try any of our Foolish newsletter services free for 30 days. We Fools may not all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors. The Motley Fool has a disclosure policy.