Although we don't believe in timing the market or panicking over market movements, we do like to keep an eye on big changes -- just in case they're material to our investing thesis.

What: Shares of Northwest Biotherapeutics (NASDAQ:NWBO), or NW Bio, a predominantly development-stage biopharmaceutical company focused on developing immunotherapies to treat cancer, surged as much as 17% after the company reported additional positive results from its phase 1/2 study involving DCVax-Direct on inoperable solid tumor cancers.

So what: According to NW Bio's early morning press release, all nine patients who have received four of the six planned DCVax-Direct injections are showing some degree of response, including tumor cell death, tumor shrinkage, and immune cell accumulation in their tumors and/or disease stabilization. Furthermore, NW Bio noted that three of these nine patients' tumor biopsies showed no live tumor cells in tumors that had been injected with DCVax-Direct. Wrapping in the company's previously reported data, this means that 13 of 20 patients who have at least received three of six injections have had some degree of disease response to the therapy, ranging from tumor cell death down to disease stabilization. As noted by NW Bio, in all cases only a single tumor in each patient is being injected, although future studies will attempt to inject DCVax-Direct into multiple tumors.

Now what: This is encouraging news, but keep in mind that we're being fed snippets of data and will probably want to hold the champagne uncorking for the end of the study. Given that NW Bio's six-injection treatment involves three injections within the first two weeks, it's no wonder that responses after three injections (just four of 11 patients) seemed fairly tame; frankly, the therapy hasn't been given a lot of time to work. However, following the fourth injection, given during week 8, and prior to a fifth injection in week 16, we're beginning to see the therapy working in select patients. In other words, there's a possibility that the drug's response rate could head even higher as more time passes. Despite this positive data, I'm personally still wary of investing in immunotherapy-focused companies following Dendreon's "failure to launch" with Provenge. However, this data is certainly encouraging enough to add NW Bio to my watchlist for the time being.

NW Bio may have soared today, but even it could struggle to keep pace with this top stock over the long run
Give us five minutes and we'll show how you could own the best stock for 2014. Every year, The Motley Fool's chief investment officer hand-picks one stock with outstanding potential. But it's not just any run-of-the-mill company. It's a stock perfectly positioned to cash in on one of the upcoming year's most lucrative trends. Last year his pick skyrocketed 134%. And previous top picks have gained upwards of 908%, 1,252% and 1,303% over the subsequent years! Believe me, you don't want to miss what could be his biggest winner yet! Just click here to download your free copy of "The Motley Fool's Top Stock for 2014" today.

Sean Williams has no material interest in any companies mentioned in this article. You can follow him on CAPS under the screen name TMFUltraLong, track every pick he makes under the screen name TrackUltraLong, and check him out on Twitter, where he goes by the handle @TMFUltraLong.

The Motley Fool has no position in any of the stocks mentioned. Try any of our Foolish newsletter services free for 30 days. We Fools may not all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors. The Motley Fool has a disclosure policy.

Compare Brokers