Make Money, Fight Cancer

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6

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One of the biggest keys to investing is figuring out which industries or trends will see substantial growth in the future. Fortunately you need not figure out if Google's (Nasdaq: GOOG) Android will beat Apple's iPhone. All you've got to do is look at demographics to find the next growth story.

The baby boomers aren't getting any younger, so we're likely to see the prevalence of cancer rise. That'll be especially true with prostate cancer, which tends to occur later in life.

As one of my biology professors was fond of saying, you've got three choices when it comes to cancer: burn it off (radiation therapy), cut it out (surgery), or poison it (chemotherapy). The treatments have become more high-tech, but the options still fall into those three categories. Let's take a look at all three options and see where investors might benefit.

Burn it off
The use of radiation is a popular option, since it doesn't involve going under the knife. Investors basically have two options: up-and coming-technologies from either smaller companies or larger, more established ones.

Varian Medical Systems (NYSE: VAR) sells a machine that claims to precisely irradiate the tumor while saving the surrounding tissue. Considering what's right next to the prostate, that sounds like a good plan to me. There's also small-cap TomoTherapy (Nasdaq: TOMO), which has a machine that looks like it's straight out of Star Trek. It integrates a CT scanner into the irradiator to more accurately pinpoint the tumor.

Of course, you could get burned if technology passes by the radiation machine. Bypass that risk by buying larger, more diverse companies like General Electric (NYSE: GE) or Siemens (NYSE: SI), both of which sell machines to radiation oncology departments.

Cut it out
Surgery hasn't exactly been the most exciting option for men with prostate cancer, since erectile dysfunction is a potential side effect of a radical prostatectomy.

That was the case until Intuitive Surgical (Nasdaq: ISRG) came out with its daVinci Surgical System. Besides the coolness factor of being operated on by a human-controlled robot, the daVinci offers some real advantages, like significantly less pain and faster recovery to potency and continence. These advantages have helped the procedure become the No. 1 treatment for prostate cancer in the U.S., according to the company.

Intuitive Surgical has developed a wide moat and doesn't have any real immediate threat from competition. Intuitive's only problem is continued expansion. As patients demand the system -- and potentially switch from radiation therapy -- there's potential to grow its own market, but the real key will be how quickly and thoroughly surgeries to operate on kidneys, bladders, and uteruses are adopted.

Poison it
There aren't too many prostate-specific chemotherapy treatments, if any. In fact, there aren't a whole lot of options for patients with a late-stage disease. That's what makes Dendreon's (Nasdaq: DNDN) Provenge so potentially lucrative.

The treatment actually involves convincing the patient's immune system to attack the tumor. This active cellular immunotherapy didn't pass muster when the company took an interim peek at that the data earlier this month, which means investors will have to wait until next year to find out if the FDA is likely to approve the drug. Personally I think that owning the stock right now is a scary proposition, but, if you're looking for a company that's almost completely invested in the prostate cancer space, Dendreon's the company you should own.

Invest in what you know
Unfortunately, almost everyone knows someone that's had prostate cancer, so Peter Lynch's axiom applies to nearly all Fools. With the aging population, now certainly could be the best time to get invested in a treatment space that's sure to grow.

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Fool contributor Brian Orelli, Ph.D., doesn't own shares of any company mentioned in this article. Apple is a choice of Stock Advisor. The Fool has a disclosure policy.

Comments from our Foolish Readers

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  • Report this Comment On November 03, 2008, at 4:16 PM, PauvrePapillon wrote:

    What?! An article about new technologies in cancer that doesn't even mention Accuray?!

    Accuray (ARAY) is the developer/manufacturer of the CyberKnife, a robotic device that treats several forms of tumors and other lesions non-invasively.

    The Star Trek-like and inspired system is highly complex and proprietary on several levels (which is a great barrier to entry for wannabe competitors) but, essentially, it all comes down to a much more precise method of radiation delivery. The CyberKnife is so accurate, in fact, that the industry has created the term “radiosurgery” to differentiate it from conventional radiation therapies.

    Accuray has been so successful in creating this whole new field of extracranial radiosurgery that Varian and others have taken to claiming that their devices are capable of SRS also. Don’t be fooled.

    Every dedicated SRS center worldwide uses CyberKnife exclusively. In fact, they aren’t even called SRS centers anymore. They are called CyberKnife Centers. Why?

    Only CyberKnife is able to attack tumors with the most optimum treatment plans, essentially a starburst like pattern of radiation that is created by multiple beams of sublethal radiation aimed from various points outside the body intersecting the tumor. Since only CyberKnife has the robotically controlled miniature linear accelerator capable of firing from any angle in any plane, all other competitors (which rely on gantry-mounted linear accelerators which can only from a single plane) are left in the dust as far as optimum treatment patterns are concerned.

    Further, only CyberKnife is able to compensate in real time for patient movement including respiration.

    Although embraced by such institutions as Stanford, Harvard and Georgetown (as well as 150 leading hospitals around the world), the technology faces resistance from old school radiation oncologists accustomed racking up their reimbursements from practices which employ primitive (but cheaper) devices that put far less radiation on the tumor and far more on the surrounding healthy tissue.

    It is just a matter of time, however, before the patient community becomes aware of the CyberKnife option. At that point, only the most trusting of fools are going to allow their doctors to blast them with conventional radiation delivery devices and the party is over for their makers - as well it should be given that the collateral damage, burns, nausea and other side-effects caused by their linacs are now, thanks to Accuray, totally unnecessary.

    If you look at Intuitive Surgical (ISRG) as the trailblazer for robotic surgical devices, it was a rocky road from IPO to $100 plus per share, but they did get there.

    From Boston’s Beth Israel Deaconess Medical Center, a leading teaching hospital of Harvard Medical School…

    “CyberKnife is a painless, non-invasive approach to radiosurgery that results in fewer complications than open surgery with comparable results.”

    Whoa! Now that’s disruptive.

    For more see: http://www.accuray.com

  • Report this Comment On November 08, 2008, at 2:24 PM, FredHutch wrote:

    I would keep an eye on this very successful new biomedical search engine - Vadlo (vadlo.com)

  • Report this Comment On November 13, 2009, at 9:38 PM, chopchop0 wrote:

    Once again, PauvrePapillon is spreading misinformation regarding gantry-based radiotherapy solutions.

    The fact is, nearly every manufacturer has a radiosurgical solution available through a conventional gantry LINAC, which of course has the ability to deliver non-coplanar beams, just like a cyberknife does.

    Of course, as any expert in PROSTATE CANCER will tell you, the CYBERKNIFE has the LEAST amount of follow-up and study out of all of the possible modalities of therapy (under 2-3 years of data from most small trials).

    Conventional IMRT has >10 years of data, and surgery series have >20-30 years of data. Most oncologists know that it takes time to tell whether a cancer is cured and whether side effects develop.

    It's no surprise that radiosurgery is not mentioned in this article, considering it is in its relative INFANCY as a treatment for prostate cancer.

    Most men will continue to choose surgery, prostate seed implants, or standard IMRT for the treatment o prostate cancer.

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