Based on the aggregated intelligence of 180,000-plus investors participating in Motley Fool CAPS, the Fool's free investing community, biotechnology company Onyx Pharmaceuticals (Nasdaq: ONXX) has received a distressing two-star ranking.

With that in mind, let's take a closer look at Onyx's business and see what CAPS investors are saying about the stock right now.

Onyx facts

Headquarters (founded) San Francisco (1992)
Market Cap $2.8 billion
Industry Biotechnology
Trailing-12-Month Revenue $452.1 million
Management CEO Dr. N. Anthony Coles (since 2008)
CFO Matthew Fust (since 2009)
Return on Equity (average, past 3 years) (2.6%)
Cash/Debt $600.0 million / $165.6 million
Competitors Genentech
Novartis
Pfizer

Sources: S&P Capital IQ and Motley Fool CAPS.

On CAPS, 14% of the 448 members who have rated Onyx believe the stock will underperform the S&P 500 going forward.

Just a few days ago, one of those Fools, All-Star zzlangerhans, nicely summed up the bear case for our community:

Onyx stock has performed strongly in recent weeks despite broad market instability. You'd think that carfilzomib approval in July would be in the bag with that kind of strength but that's not how I read the pundits. [Onyx] is shooting for accelerated approval of carfilzomib but they didn't get priority review and efficacy was marginal, especially when strict criteria for unmet medical need are applied.

Meanwhile, the company continues to lose money briskly and Nexavar has shown no sign of broadening its appeal beyond kidney and liver cancer. [Onyx] still has many shots on goal in their future, but I think the goalie is in good position to block the next one.

If you want market-thumping returns, you need to protect your portfolio from any undue risk. Luckily, we've compiled a special free report for investors called "Discover the Next Rule-Breaking Multibagger," which uncovers another small-cap growth play with big potential. The report is 100% free, but it won't be around forever, so click here to access it now.

Want to see how well (or not so well) the stocks in this series are performing? Follow the new TrackPoisedTo CAPS account.