The following is a direct quote: "if they cant tell you what will go up 100% in a few days then motley fool are worthless and they suck at picking stocks."

I received that comment on one of my recent columns. Grammar issues aside, this type of get-rich-quick mentality scares the heck out of me.

Now, don't get me wrong. I enjoy stalking monster returns. Heck, I'll even reveal your best shot at snaring a 10-bagger a little later in this piece. But first, let me warn you against an investing mistake that leads to many a zero-bagger.

The warning
My worst investing decisions have involved three common elements:

  • The allure of great upside.
  • The "need" to act quickly.
  • The lack of proper due diligence.

My visions of huge, unrealistic profits led to hasty decision-making, which led to losses. In other words, almost every time I've tried to swing out of my shoes to hit a home run, I've struck out.

To defend yourself against the kind of greed that leads to grief, put investing returns in perspective.

My critic earlier talked about 100% returns in just a few days. Let's think through that for a minute. If you started with $10,000 and made 100% gains every week, you'd be the richest person in the world -- surpassing Bill Gates' $40 billion -- in far less than six months.

I'll go one step further. Perhaps you're thinking of the huge gains we've had over the course of the last year. If you timed it right, you could have made more than 100% on Halliburton (NYSE:HAL) and Chesapeake Energy (NYSE:CHK), more than 150% on General Electric (NYSE:GE) and Alcoa (NYSE:AA), or more than 1,500% on Human Genome Sciences (NASDAQ:HGSI).

Although these are real returns some investors have achieved, they're not the sort of realistic earnings anyone can expect over the long term. You can't extrapolate Usain Bolt's 100-meter times to conclude that he could run a marathon in 70 minutes. Similarly, even the best investors can't generate 100% returns year after year.

What's the upper limit of reasonable?
Peter Lynch is recognized as one of the greatest investors of all time. He ran his Fidelity Magellan Fund from 1977 to 1990 -- less than 15 years, during one hell of a bull market. Even in those perfect conditions, he "only" averaged 29% annual returns.

If you're wondering about Warren Buffett, his returns are lower than Lynch's. If you got in on his company, Berkshire Hathaway, in 1965, you'd have generated average annual returns in the neighborhood of 20%.

Now, because of the power of compounding for 45 years, those returns are tremendous. A $10,000 investment back then would leave you a millionaire many times over.

Believing you can do much better than the 20% to 30% long-term annual returns of Lynch and Buffett is almost surely a road to overconfidence and failure. Doing half of what they did would make you a very, very rich investor.

Your best shot at a 10-bagger
Now that we're grounded in reality, let's talk about what it takes to snag a 10-bagger in 10 years, while limiting your risk.

For a stock to be worth 10 times its buy-in price in 10 years requires a 26% annual return. As the returns of Lynch and Buffett attest, that's huge! 

Going after that kind of return, even in an individual stock, isn't for everyone. You have to have a mighty risk tolerance. That's why most people are best served allocating among index funds or ETFs, and holding for the long haul. In fact, I believe everyone this side of Buffett and Lynch should index at the core of their portfolios.

But for those of us who want to pick some individual stocks and go after a 10-bagger or two, small-cap stocks (i.e., stocks with market caps of $2 billion or less) are our best shot.

Large-cap stocks like Cisco (NASDAQ:CSCO) ($139 billion market cap) and Pfizer (NYSE:PFE) ($142 billion market cap) simply don't have the room to grow that their $2-billion-and-under brethren do. Now, large caps have their place in your portfolio, but that place isn't in the area dedicated to the 10-bagger.

To maximize your chances of achieving a 10-bagger in 10 years without throwing Hail Marys, focus on smaller companies that have:

  • Strong balance sheets.
  • Strong cash flows.
  • Strong growth prospects.

Our small-cap experts at Hidden Gems have recommended Dynamic Materials, a maker of explosion-welded clad metal plates, to their members. This stock is a good place to start your 10-bagger research. To see the Hidden Gems team's entire write-up on Dynamic Materials, and the rest of their recommendations, click here for a free 30-day trial.

Anand Chokkavelu owns shares of Pfizer and Halliburton. He made a 100% return in just two days once: The sweater didn't fit, and he got store credit. Chesapeake Energy and Pfizer are Motley Fool Inside Value recommendations. The Fool owns shares of Chesapeake Energy. The Fool has a disclosure policy.