Is There a "First-Mover" Advantage in Biotech?http://www.fool.com/investing/general/2013/03/06/is-there-a-first-mover-advantage-in-biotech.aspx Keith Speights
March 6, 2013
The early bird gets the worm. Business gurus might not use that old phrase, but many of them tout the principle behind it. They tell anyone who will listen that getting to market first provides significant advantages. Customers will gain familiarity with the first product on the market and be much less likely to switch to another product later. That's what the gurus say, but is it true?
One biotech that certainly hopes they're right is VIVUS (NASDAQ: VVUS). The company's weight loss drug Qsymia gained FDA approval last July. VIVUS quickly moved to launch the drug, with Qsymia reaching the market in September.
However, Arena Pharmaceuticals (NASDAQ: ARNA) is nipping at its heels. Arena's Belviq actually gained FDA approval a few weeks earlier than Qsymia. The company hasn't been able to launch the drug commercially, though, as it awaits scheduling by the Drug Enforcement Agency.
Will VIVUS be able to benefit from a first-mover advantage? Or is this concept really not applicable to biotech?
Birds of a different feather
By any measure, Enbrel was a huge success. But another TNF inhibitor followed closely in its footsteps. Johnson & Johnson's (NYSE: JNJ) Remicade gained FDA approval for treating rheumatoid arthritis in 1999. The two drugs battled it out by themselves until 2002, when the FDA approved AbbVie's (NYSE: ABBV) Humira.
So, how well did Amgen's first-mover advantage hold up? If we fast forward the clock to 2012, the sales for the three drugs tell the story. Amgen made $4.2 billion from Enbrel. Add to that figure another $3.7 billion from Pfizer's (NYSE: PFE) sales of Enbrel outside the U.S. That gives Enbrel a total of $7.9 billion in 2012 sales.
Second-to-market Remicade trailed Enbrel with $6.1 billion in sales. AbbVie's 2012 sales for Humira totaled $9.3 billion, making it the world's top-selling drug. While Enbrel and Remicade also rank in the top five drugs in terms of worldwide sales, the laggard in getting to market became the leader.
One slippery worm
U.S. sales for Qsymia have been disappointing -- only around $2 million in 201