In the following video, Motley Fool financial analysts Matt Koppenheffer and David Hanson take a look at Bank of America (BAC 1.28%) over the course of the last 15 years and discuss why this bank lost money for investors who held it over that long-term period, even including dividends.

While Bank of America was not the worst-performing big bank over that time period, Matt highlights two big high-risk acquisitions the bank made, of Countrywide and Merrill Lynch, that brought the bank's performance down significantly over that period.