Ugh, ugh, and ugh. Quite a few stocks got hit hard this week, but few like three especially unlucky health-care stocks. April Fools' Day is over, but shareholders of this week's big losers probably still feel like someone is pulling a prank on them.

One of this week's ugliest stocks felt the repercussions of having to halt a clinical study because of potential safety concerns. Another is a former high-flying IPO stock that continues to see the wind abandoning its sails. The third felt the agony of potential defeat being snatched from the jaws of victory by a Supreme Court decision.

Which stocks made this week's list of horrendous performers? Check out the following slideshow to find out.