Recs

8

This Just In: Upgrades and Downgrades

Watch stocks you care about

The single, easiest way to keep track of all the stocks that matter...

Your own personalized stock watchlist!

It's a 100% FREE Motley Fool service...

Click Here Now

At The Motley Fool, we poke plenty of fun at Wall Street analysts and their endless cycle of upgrades, downgrades, and "initiating coverage at neutral." Today, we'll show you whether those bigwigs actually know what they're talking about. To help, we've enlisted Motley Fool CAPS to track the long-term performance of Wall Street's best and worst.

Summer Street rains on Seattle Genetics' parade
"There's no such thing as bad publicity," goes the old saw. And if that's true, shareholders of cancer fighter Seattle Genetics (Nasdaq: SGEN  ) should be dancing in the streets. Earlier this week, the stock was featured alongside peers Aastrom Biosciences (Nasdaq: ASTM  ) , Regeneron (Nasdaq: REGN  ) , and MannKind (Nasdaq: MNKD  ) in a Seeking Alpha list of "15 biotech stocks being snapped up by company insiders." That same day, S-Gen also appeared in a second article (this time, on TheStreet.com) scoring the 10 most shorted stocks in biotech, alongside Savient (Nasdaq: SVNT  ) and Avanir Pharma (Nasdaq: AVNR  ) . Today, however, I'm going to take a look at Seattle Genetics' third appearance on investors' radar screens this week, when Summer Street Research initiated coverage of the stock yesterday ... and told investors to dump the stock.

S-Gen shares currently fetch $21 apiece, you see. But Summer Street sees them dropping to $12 within just a few months. If you think that's harsh, though, consider: Even at Summer's price target, S-Gen shares would cost 5 times book value, and 27 times sales. Those are valuations high enough to make Dendreon (3 times book and 11 times sales) look cheap! And you already know what I think about Dendreon's (Nasdaq: DNDN  ) valuation.

Bull in a cancer shop
Mind you, this is not to say that Seattle Genetics doesn't have a bright future -- as a company. Indeed, just this past summer, S-Gen received permission from the FDA to begin marketing its Adcetris lymphoma treatment. The Fool's own Brian Orelli characterized the approval as "giving credence to the technology" and opening the way for S-Gen to continue developing and marketing more and more drugs based on its antibody-drug conjugates technology.

Here's hoping ... but optimistic as I am that S-Gen has opened a new -- and effective -- front in the war against cancer, I still can't justify the price investors are paying for this stock. I mean, does FDA approval mean sales will grow? Sure it does. But we're still talking about growth off a revenue base that's only $50 million strong, annually. And this is a company that's ...

  • Burning cash at a frenetic pace (more than $80 million in negative free cash flow over the past 12 months).
  • Not currently earning any GAAP profits at all.
  • Expected by most analysts to continue losing money for at least three more years.
  • Hoping to turn a profit in 2014 largely on the success of a drug that costs $108,000 per patient.

For the record, that's a price tag $15,000 higher than Provenge costs -- and I suspect you've heard how that pricing strategy worked out for Dendreon.

Foolish takeaway
Fools, the math here just isn't that complicated. At 48 times sales, and infinity times earnings-that-aren't, Seattle Genetics shares have a lot of investor hope built into their valuation -- but no guarantee that this hope will ever be rewarded. The shares may sell for 4 times Dendreon's P/S today, and 3 times its P/B, but ultimately, I expect Seattle Genetics will share Dendreon's fate.

My advice: Hold on if you're willing to accept the risk of a 65% drop. Take Summer Street's advice and sell if you aren't.

Disagree? Think Seattle Genetics will escape Dendreon's fate? Add it to your Fool Watchlist, and read along as it tries.

The Steve Jobs Betrayal
You may already know that in the final year of his life, Jobs revealed a stunning betrayal — and told his biographer, "I will spend my last dying breath... and every penny of Apple's $40 billion in the bank to right this wrong." What was it that made Jobs so irate — and why could it make a few in-the-know investors some major profits over the coming months and years?

Enter your email address below to find out what made Jobs so enraged!

Fool contributor Rich Smith does not own (or short) shares of any company named above, but The Motley Fool owns shares of Dendreon. You can find Rich on CAPS, publicly pontificating under the handle TMFDitty, where he's currently ranked No. 311 out of more than 180,000 members. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors. The Motley Fool has a disclosure policy.


Comments from our Foolish Readers

Help us keep this a respectfully Foolish area! This is a place for our readers to discuss, debate, and learn more about the Foolish investing topic you read about above. Help us keep it clean and safe. If you believe a comment is abusive or otherwise violates our Fool's Rules, please report it via the Report this Comment Report this Comment icon found on every comment.

  • Report this Comment On October 07, 2011, at 7:33 AM, exwannabe wrote:

    Regardless of what one thinks of SGEN as an investment, evaluating dev stage biotechs based on earnings before they have a single product being sold is comical.

    Burn rate is a very valid issue. But for SGEN once you add in Acetris revenue the burn will be down to a very small amount relative to cash.

    The price of the drug is not an issue. The problem with Provenge was the up-front and lump sum nature of the payment (on top of the price and reimbursement issues that many drugs have).

    The valuation of SGEN is mainly based on what the technology and dozens of candidates now in trials are worth. It is of course difficult for you to evaluate this when your only metrics are based on sales.

Add your comment.

Compare Brokers

Fool Disclosure

DocumentId: 1565882, ~/Articles/ArticleHandler.aspx, 5/26/2012 3:47:56 PM

Report This Comment

Use this area to report a comment that you believe is in violation of the community guidelines. Our team will review the entry and take any appropriate action.

Sending report...

Today's Market

updated 18 hours ago Sponsored by:
DOW 12,454.83 -74.92 -0.60%
S&P 500 1,317.82 -2.86 -0.22%
NASD 2,837.53 -1.85 -0.07%

Create My Watchlist

Go to My Watchlist

You don't seem to be following any stocks yet!

Better investing starts with a watchlist. Now you can create a personalized watchlist and get immediate access to the personalized information you need to make successful investing decisions.

Data delayed up to 5 minutes

Related Tickers

5/25/2012 4:00 PM
REGN $132.17 Up +2.46 +1.90%
Regeneron Pharmace… CAPS Rating: *
SGEN $20.57 Down -0.08 -0.39%
Seattle Genetics,… CAPS Rating: ***
SVNT $0.86 Up +0.10 +13.05%
Savient Pharmaceut… CAPS Rating: ***
MNKD $1.71 Up +0.01 +0.59%
MannKind Corp CAPS Rating: **
ASTM $2.05 Down -0.01 -0.49%
AASTROM BIOSCIENCE… CAPS Rating: *
AVNR $2.84 Up +0.02 +0.71%
AVANIR PHARMACEUTI… CAPS Rating: **
DNDN $7.11 Down -0.11 -1.52%
Dendreon Corp CAPS Rating: **

Advertisement