While Express Scripts (ESRX), the largest pharmacy benefit manager in the country, has a firm grip on its industry, investors have been more concerned with getting a grip on the company's prospects for the future, especially after a negative outlook sent shares south late last year. In the following video, Motley Fool health care bureau chief quickly runs through his assessment of Express Scripts' guidance and discusses a few tailwinds and headwinds facing the company in the near future.