In the spirit of World Cup competition, we're holding our own tournament in search of the Better Stock Today. We're pitting 32 companies against each other, and you, the reader, will determine the winner.

Celgene takes on American Express for this first round-robin match up in our search for the better stock today.

Health-care analyst David Williamson believes the No. 1 reason Celgene (NASDAQ:CELG) should win this match is its ability to open new sales possibilities for already approved drugs. By expanding indications -- i.e., having drugs used for multiple diseases -- management expects to double earnings from 2013 to 2017. Headlined by megablockbuster Revlimid, this big biotech is an oncology and autoimmune powerhouse stock that's showing no signs of slowing down.

Financials analyst Tyler Riggs believes the No. 1 reason American Express (NYSE:AXP) is the strongest buy in the field is the company's extremely strong competitive position and -- most importantly -- what this means for the future of credit cards and payments. In terms of strength, American Express is unmatched in the credit card industry, with its focus on just a key segment of cardholders: those who are more affluent, which means less risk and more spending. In addition, the company's unique closed-loop system puts it in an incredible position to capitalize on the changing payments landscape.

Warren Buffett vs. his worst nightmare 
Warren Buffett just called this emerging technology a "real threat" to his biggest cash cow. While Buffett shakes in his billionaire boots, only a few investors are embracing this new market, which experts say will be worth over $2 trillion. It won't be long before everyone on Wall Street wises up, and that's why The Motley Fool is releasing this timely investor alert. Click here to learn more about what's keeping Buffett up at night and the one public company we're calling the brains behind the technology.

Vote here to determine the winner of this match, and sound off in the comments. Check back to to see who advances in the tournament.

David Williamson and Tyler Riggs have no position in any stocks mentioned. The Motley Fool recommends American Express and Celgene. Try any of our Foolish newsletter services free for 30 days. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors. The Motley Fool has a disclosure policy.