Investors took off exposure to Exact Sciences (EXAS -7.04%) in September ahead of a key update to colon cancer screening and that decision appears to have been the right one given that guidelines announced this month failed to include Exact Sciences' Cologuard.

In the following slideshow, you'll learn why this update to guidelines was important for Exact Sciences and the risks that its investors continue to face.

The next billion-dollar iSecret
The world's biggest tech company forgot to show you something at its recent event, but a few Wall Street analysts and the Fool didn't miss a beat: There's a small company that's powering their brand-new gadgets and the coming revolution in technology. And we think its stock price has nearly unlimited room to run for early in-the-know investors! To be one of them, just click here.