Although we don't believe in timing the market or panicking over market movements, we do like to keep an eye on big changes -- just in case they're material to our investing thesis.

What: Ariad Pharmaceuticals (Nasdaq: ARIA) shares have jumped 14% higher as investors make big bets on the stock heading into the new year.

So what: The company didn't release any news, but the stock has been actively traded and options are pointing to bullish signs. Option volume is nearly 8:1 calls to puts, indicating a very bullish bet by investors, and stock volume is more than double the three-month average.

Now what: Investors are placing bets ahead of Ridaforolimus Phase 3 SUCCEED trial data, which should be released early next year. There doesn't seem to be any letup from the run Ariad has been on since mid-November, when the stock started to climb sharply higher. Option volume would indicate there is still some momentum left in the stock as the SUCCEED trial nears an end.

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