Exelixis Shares Got Decimated: What You Need to Know

Although we don't believe in timing the market or panicking over market movements, we do like to keep an eye on big changes -- just in case they're material to our investing thesis.

What: Shares of biotech Exelixis (Nasdaq: EXEL  ) are being dumped like the plague today, down by as much as a gut-wrenching 41% so far, after the company failed to reach an agreement with regulators over special rules with its phase 3 trial.

So what: The drug in question, cabozantinib, is an experimental prostate cancer drug, and the company plans on measuring its effectiveness by pain reduction in the trial. Exelixis has decided to proceed with the study since it is in the company's best interest, despite lacking regulators' blessings.

Now what: Exelixis is looking to initiate the trial by year's end, and a different trial to measure overall survival in the first half of 2012. The company indicated that leading investigators and consultants advised it to proceed, since it would be in the best interests of patients and Exelixis to initiate the trial as soon as possible. It's a risky move to proceed without getting regulators to sign off on the trial, but biotech investors should be no strangers to risk.

Interested in more info on Exelixis? Add it to your watchlist by clicking here.

Fool contributor Evan Niu holds no position in any company mentioned. Click here to see his holdings and a short bio. The Motley Fool owns shares of Exelixis. Motley Fool newsletter services have recommended buying shares of Exelixis. Try any of our Foolish newsletter services free for 30 days. We Fools may not all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors. The Motley Fool has a disclosure policy.


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  • Report this Comment On November 01, 2011, at 5:32 PM, mwlove wrote:

    Etymologically, "decimated" means that 1 in 10 gets killed. The word derives from the Roman practice of killing one of every ten soldiers from units that fled in battle. Today was much worse for Exelisis. Even so, Exelisis owners are used to this sort of thing. I still think it will all work out.

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