Eli Lilly and Partner Show Positive Diabetes Data in 4 Trials

Eli Lilly (NYSE: LLY  ) and partner Boehringer Ingelheim today announced positive results for no less than four phase 3 trials for their diabetes drug empagliflozin.

The trials, which enrolled more than 3,700 patients, compared empagliflozin by itself or in combination with other diabetes medications to placebo. In all four trials, the drug decreased patients' HbA1c, a measure of long-term blood sugar levels, from baseline compared to placebo. The companies plan to present the full data from the trials at upcoming medical meetings and in scientific journals.

Empagliflozin is an inhibitor of sodium glucose cotransporter-2, or SGLT-2, the same class of drug as Bristol-Myers Squibb  (NYSE: BMY  ) and AstraZeneca's (NYSE: AZN) dapagliflozin, which was rejected by the Food and Drug Administration last year. Mitsubishi Tanabe Pharma and Johnson & Johnson (NYSE: JNJ  ) also have an SGLT-2 inhibitor, canagliflozin, under FDA review.

Eli Lilly and Boehringer Ingelheim plan to submit applications for regulatory review in the U.S., Europe, and Japan in 2013.


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  • Report this Comment On January 08, 2013, at 10:04 AM, DannyHaszard wrote:

    Zyprexa Diabetes connection conflict of interest.

    Eli Lilly paid billions in fines for the scam.

    Thousands got diabetes as Zyprexa side effect and have to take Lilly insulin to treat the diabetes that was caused by their Zyprexa.

    Eli Lilly Zyprexa can ruin your Pancreas and make you a type 2 diabetic in just a few months of use.I took it 1996-2000 and now am a diabetic for it.

    -Daniel Haszard

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