Will Orexigen Have the Last Laugh?

When looking at the obesity drug space, investors tend to focus on VIVUS' (NASDAQ: VVUS  ) Qsymia and Arena Pharmaceuticals' (NASDAQ: ARNA  )  Belviq.

But have they already forgotten about the third potential player: Orexigen Therapeutics (NASDAQ: OREX  ) ?

Orexigen's success hinges on approval from the Food and Drug Administration on its weight-loss drug Contrave, and the company released news today that suggests it is inching its way closer to a final decision. In the following video, health care analyst Max Macaluso breaks down the news, explains why shares of Orexigen were static today, and also notes one major risk that investors can't ignore with this stock.

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Read/Post Comments (12) | Recommend This Article (1)

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  • Report this Comment On January 07, 2013, at 3:17 PM, RSRdriver wrote:

    Even though something tells me your mom's basement is behind that screen, you actually make a lot of good points.

    When one looks at the Vivus/J+J lawsuit potential and Arena's efficacy and Eisai entanglements, OREX is really the only real buyout candidate as well.

  • Report this Comment On January 07, 2013, at 5:23 PM, TMFMassimo wrote:

    @RSRdriver, thanks for the comment! In terms of a potential buy-out, it's important to note that Orexigen has a partnership agreement in place with Takeda for the commercialization of Contrave.

  • Report this Comment On January 08, 2013, at 10:08 AM, Jinmeif88 wrote:

    Just forget about Contrave for a while. The required testing procedures will not complete until early 2014 plus the time to resubmit the application -- and the FDA review time, --- So take a nap, a good nap for that one.

  • Report this Comment On January 08, 2013, at 12:32 PM, RSRdriver wrote:

    The play on OREX is into the event stage which should start this quarter. No one here is recomending a long term investment. If you don't know what a trade is, stick to the BS slinging on the ARNA message boards.

  • Report this Comment On January 08, 2013, at 1:04 PM, MannyGoldberg wrote:

    I am an experienced Bariatric Physician, well versed in medical treatment of obesity, as well as FDA approval, as a former Principla Investigator.

    It is humorous to read the author's positive comments about Contrave, which is a long way from FDA approval. I recoomend you take a Wellbutrin daily as well as Narcan daily for a week, and report back how you feel.

    Wellbutrin makes many patients feel like a "zombie" and Narcan will reverse any pain-relieving narcotic like medications, throwing them into "cold turkey" withdrawal pain..

    Can you see a zombie in pain actually wanting to refill a Rx for Contrave, even if it is approved?

  • Report this Comment On January 08, 2013, at 1:09 PM, RSRdriver wrote:

    Another Areniac "doctor". Just what ARNA longs need.

    You guys do more harm to the PPS than the puny efficacy. Keep it coming DH's.

  • Report this Comment On January 08, 2013, at 1:22 PM, MannyGoldberg wrote:

    RS Driver,

    You are right........ I have over 250 patients (many are also diabetics) I plan to start on Belviq (I already have over 50 on Qsymia). I hate writing Rxs for Qsymia, like many M.D.s, but many I plan to switch to Belviq when they plateau. Contrave I dont ever plan to use, like many of my bariatric colleagues,

  • Report this Comment On January 08, 2013, at 1:25 PM, RSRdriver wrote:

    This Areniac BS is getting old. Try that crap over at the Yahoo Message board.

  • Report this Comment On January 08, 2013, at 1:26 PM, MannyGoldberg wrote:

    RS Driver,

    One more thing.....the efficacy issue is solid with Belviq....8% in a year, with 25% losing over 16%! This might not sound like much to the lay public, but it definitely makes a huge difference in

    blood sugar control, back pain, sleep apnea, and the horrible chronic pain of osteoarthritis.

  • Report this Comment On January 08, 2013, at 1:30 PM, RSRdriver wrote:

    I see your slinging Reza's numbers. You guy's are hilarious. EVERYONE KNOWS BELVIQ IS USELESS!

  • Report this Comment On January 08, 2013, at 1:36 PM, MannyGoldberg wrote:

    Sounds like you are already taking Contrave.....LOL.

    Unfortunately for you, you are wrong, but you won't be writing the Rxs, will you?.....

    Guess who will??

  • Report this Comment On January 08, 2013, at 1:45 PM, RSRdriver wrote:

    You know, there SEC laws in place that are specifically used to cover fraud by impersonation. Check them out.

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