Track the companies that matter to you. It's FREE! Click one of these fan favorites to get started: Apple; Google; Ford.



Vanda Drug Fails in Depression Study

Biotech firm Vanda Pharmaceuticals (NASDAQ: VNDA  ) announced in a press statement Thursday that a phase 2b/phase 3 clinical trial studying the efficacy and safety of the drug tasimelteon in treating major depressive disorder (MDD) failed to meet its primary endpoints. The company has thus ended its program of targeting tasimelteon as a treatment for MDD.

The trial showed the drug to be safe, but tasimelteon only performed about as well as a placebo in reducing MDD symptoms in patients. Each managed to post around a 40% reduction in symptoms from a baseline.

Vanda CEO and President Dr. Mihael H. Polymeropoulos was quoted in the press release as saying, "These results are disappointing, as there is still a significant unmet medical need for patients with Major Depression." However, he said Tasimelteon's application in the treatment of blind individuals with non-24-hour sleep-wake disorder, a chronic circadian rhythm sleep disorder, remains the company's "top priority" as it aims for a New Drug Application submission in the middle of this year.

Read/Post Comments (0) | Recommend This Article (0)

Comments from our Foolish Readers

Help us keep this a respectfully Foolish area! This is a place for our readers to discuss, debate, and learn more about the Foolish investing topic you read about above. Help us keep it clean and safe. If you believe a comment is abusive or otherwise violates our Fool's Rules, please report it via the Report this Comment Report this Comment icon found on every comment.

Be the first one to comment on this article.

Compare Brokers

Fool Disclosure

Sponsored Links

Leaked: Apple's Next Smart Device
(Warning, it may shock you)
The secret is out... experts are predicting 458 million of these types of devices will be sold per year. 1 hyper-growth company stands to rake in maximum profit - and it's NOT Apple. Show me Apple's new smart gizmo!

DocumentId: 2230632, ~/Articles/ArticleHandler.aspx, 9/30/2016 6:19:51 AM

Report This Comment

Use this area to report a comment that you believe is in violation of the community guidelines. Our team will review the entry and take any appropriate action.

Sending report...

Today's Market

updated 9 hours ago Sponsored by:
DOW 18,143.45 -195.79 -1.07%
S&P 500 2,151.13 -20.24 -0.93%
NASD 5,269.15 -49.39 -0.93%

Create My Watchlist

Go to My Watchlist

You don't seem to be following any stocks yet!

Better investing starts with a watchlist. Now you can create a personalized watchlist and get immediate access to the personalized information you need to make successful investing decisions.

Data delayed up to 5 minutes

Related Tickers

9/29/2016 4:00 PM
VNDA $16.26 Down -0.44 -2.63%
Vanda Pharmaceutic… CAPS Rating: *