Although we don't believe in timing the market or panicking over market movements, we do like to keep an eye on big changes -- just in case they're material to our investing thesis.

What: Shares of biopharmaceutical company Optimer Pharmaceuticals (NASDAQ: OPTR) rose by as much as 24% after a Bloomberg report cited that interested bidders in the company could include GlaxoSmithKline, AstraZeneca, Cubist Pharmaceuticals, and Astellas Pharma.

So what: The news of interest in Optimer -- which has one approved drug in Dificid for the treatment of Clostridium difficile-associated diarrhea -- shouldn't be any surprise as the company jumped higher in late February when it announced it had planned a strategic review for the company. According to people familiar with the matter, Optimer could draw as much as $1 billion in value. As you might imagine, not a single company was willing to comment on these "rumors."

Now what: As I said back in February, with only one drug currently on the market, any buyer would be crazy to pay a significant premium just to get their hands on Dificid. Based on the $154 million sales estimate by Wall Street in 2014, I can't imagine Dificid sales getting much past $200 million to $225 million at their peak. In short, what large pharmaceutical is going to pay more than three times peak sales for one drug? Not too many that I know of, which is why I'd suggest backing away from Optimer.

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