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Obesity was the focus of this segment from The Motley Fool's health-care show, Market Checkup. More than 35% of Americans are obese, and obesity can lead to serious health problems, including diabetes, stroke, and heart disease. The AMA also recently classified obesity as an official disease.

In this video, health-care analysts David Williamson and Max Macaluso discuss how two Big Pharma companies -- Novo Nordisk (NVO -0.29%) and AstraZeneca (AZN 5.38%) -- might become the next major players in the obesity space.(AZN 5.38%)