The following video is from Wednesday's edition of Investor Beat, in which host Chris Hill and Motley Fool analysts Jason Moser and Matt Argersinger dissect the hardest-hitting investing stories of the day.

Shares of MAKO Surgical (MAKO.DL) skyrocketed on news that Stryker (SYK 0.58%) will acquire the company for $1.65 billion in cash. AutoZone (AZO 0.93%) shares were bolstered slightly by news that fourth-quarter profits rose 15%. J.C. Penney (JCPN.Q) hits a 13-year low on news of a Goldman Sachs downgrade. And Chinese online media company SINA (SINA) continues its rise, now up more than 60% YTD. In this segment, Matt and Jason look at four stocks making big moves today.