Amgen Inc’s Next Blockbuster Drug Delivers

Here's what's behind the headlines with Amgen's next blockbuster drug.

Jan 23, 2014 at 8:18PM

On Thursday's edition of Market Checkup, The Motley Fool's health-care focused show for investors, Fool health-care analyst David Williamson sheds some light on what's driving the biggest movers in the health-care space today.

Amgen (NASDAQ:AMGN) has just released phase 3 data for its PCSK9 drug, AMG 145, and the results are impressive. Drugs that aim to block the PCSK9 enzyme have the potential to lower cholesterol levels in patients, and AMG 145 has met both of its phase 3 endpoints while remaining relatively well-tolerated by the trial patients. In a phase 2 trial, AMG 145, also called evolocumab, led to a 51% reduction in LDL levels, which rose to a 63% reduction when combined with a statin. David emphasizes just how much more effective this is than the currently available treatments on the market, and discusses why this drug could be a multi-billion dollar blockbuster. He also discusses some of Amgen's competitors, and tells investors who else could be affected as this drug potentially makes its way to market.

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David Williamson owns shares of Merck and Pfizer. The Motley Fool has no position in any of the stocks mentioned. Try any of our Foolish newsletter services free for 30 days. We Fools may not all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors. The Motley Fool has a disclosure policy.

4 in 5 Americans Are Ignoring Buffett's Warning

Don't be one of them.

Jun 12, 2015 at 5:01PM

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The catch was: Attendees weren't allowed to record any of it. No audio. No video. 

Our team of analysts wrote down every single word Buffett and Munger uttered. Over 16,000 words. But only two words stood out to me as I read the detailed transcript of the event: "Real threat."

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KPMG advises we're "on the cusp of revolutionary change" coming much "sooner than you think."

Even one legendary MIT professor had to recant his position that the technology was "beyond the capability of computer science." (He recently confessed to The Wall Street Journal that he's now a believer and amazed "how quickly this technology caught on.")

Yet according to one J.D. Power and Associates survey, only 1 in 5 Americans are even interested in this technology, much less ready to invest in it. Needless to say, you haven't missed your window of opportunity. 

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David Hanson owns shares of Berkshire Hathaway and American Express. The Motley Fool recommends and owns shares of Berkshire Hathaway, Google, and Coca-Cola.We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors. The Motley Fool has a disclosure policy.

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