Track the companies that matter to you. It's FREE! Click one of these fan favorites to get started: Apple; Google; Ford.



Why Idera Pharmaceuticals Inc. Shares Jumped

Don't let it get away!

Keep track of the stocks that matter to you.

Help yourself with the Fool's FREE and easy new watchlist service today.

Although we don't believe in timing the market or panicking over market movements, we do like to keep an eye on big changes -- just in case they're material to our investing thesis.

What: Shares of Idera Pharmaceuticals (NASDAQ: IDRA  ) , a clinical-stage biopharmaceutical company developing DNA- and RNA-based therapies, jumped by as much as 22% after announcing positive top-line data from its midstage study of IMO-8400 as a treatment for moderate-to-severe plaque psoriasis.

So what: According to Idera's press release, in its 32 patient phase 2 study IMO-8400 met both its primary and secondary endpoint, which was the evaluation of the safety and tolerability of the therapy, and the evaluation of the clinical activity of the drug. The release notes that the treatment was well tolerated with no "no treatment related discontinuation, serious adverse events or dose reductions." Clinical activity was measured by the Psoriasis Area and Severity Index (PASI). A score of PASI 50 (implying a 50% improvement compared to baseline at week 12) was achieved in nine of 20 patients at all doses compared to just one in seven for the placebo.

Now what: Today's results are obviously important for Idera for two key reasons. First, plaque psoriasis is the most common form of psoriasis, leaving it a potentially large target audience if IMO-8400 continues to perform well in trials and is eventually approved. Secondly, and perhaps most importantly, it validates the clinical mechanism behind IMO-8400 and could potentially put the company on the radar of a larger pharmaceutical company looking to license out this development in the U.S. or abroad. I'd certainly prefer to see the full data set as opposed to just the top-line data before getting too excited, but I wouldn't argue against Idera working its way onto your watchlist in the meantime.

Idera may be soaring today, but it'll likely have a hard time keeping up with this top stock in 2014
There's a huge difference between a good stock and a stock that can make you rich. The Motley Fool's chief investment officer has selected his No. 1 stock for 2014, and it's one of those stocks that could make you rich. You can find out which stock it is in the special free report "The Motley Fool's Top Stock for 2014." Just click here to access the report and find out the name of this under-the-radar company.

Read/Post Comments (0) | Recommend This Article (1)

Comments from our Foolish Readers

Help us keep this a respectfully Foolish area! This is a place for our readers to discuss, debate, and learn more about the Foolish investing topic you read about above. Help us keep it clean and safe. If you believe a comment is abusive or otherwise violates our Fool's Rules, please report it via the Report this Comment Report this Comment icon found on every comment.

Be the first one to comment on this article.

Sponsored Links

Leaked: Apple's Next Smart Device
(Warning, it may shock you)
The secret is out... experts are predicting 458 million of these types of devices will be sold per year. 1 hyper-growth company stands to rake in maximum profit - and it's NOT Apple. Show me Apple's new smart gizmo!

DocumentId: 2894817, ~/Articles/ArticleHandler.aspx, 8/29/2015 5:47:00 AM

Report This Comment

Use this area to report a comment that you believe is in violation of the community guidelines. Our team will review the entry and take any appropriate action.

Sending report...

Sean Williams

A Fool since 2010, and a graduate from UC San Diego with a B.A. in Economics, Sean specializes in the healthcare sector and in investment planning topics. You'll usually find him writing about Obamacare, marijuana, developing drugs, diagnostics, and medical devices, Social Security, taxes, or any number of other macroeconomic issues.

Today's Market

updated 8 hours ago Sponsored by:
DOW 16,643.01 -11.76 -0.07%
S&P 500 1,988.87 1.21 0.06%
NASD 4,828.33 15.62 0.32%

Create My Watchlist

Go to My Watchlist

You don't seem to be following any stocks yet!

Better investing starts with a watchlist. Now you can create a personalized watchlist and get immediate access to the personalized information you need to make successful investing decisions.

Data delayed up to 5 minutes

Related Tickers

8/28/2015 4:00 PM
IDRA $2.92 Up +0.03 +1.04%
Idera Pharmaceutic… CAPS Rating: **