Celgene's (NASDAQ:CELG) new psoriatic arthritis drug Otezla isn't going to beat the current offerings from AbbVie (NYSE:ABBV), Johnson & Johnson (NYSE:JNJ), and Amgen (NASDAQ:AMGN) on an efficacy basis.

But it doesn't have too. Unlike Humira, Remicade, Enbrel, and the rest of the injected or infused biologics, Otezla is taken orally, giving Celgene a distinct advantage over AbbVie, Johnson & Johnson, and Amgen.

That doesn't mean Otezla will be an instant blockbuster though. As Fool contributor Brian Orelli and health-care bureau chief Max Macaluso discuss in the video below, Celgene needs to find a sweat spot, positioning Otezla between oral generics and the biologics doctors are comfortable prescribing.

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Brian Orelli has no position in any stocks mentioned. Max Macaluso, Ph.D., owns shares of Celgene. The Motley Fool recommends Celgene and Johnson & Johnson. The Motley Fool owns shares of Johnson & Johnson. Try any of our Foolish newsletter services free for 30 days. We Fools may not all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors. The Motley Fool has a disclosure policy.