This week's tweet of the week comes from Frank David, who points out a fact he learned in an article by Matthew Herper: Over half of companies that got a drug approved by the FDA from 1950 to 2011 did so only once.

In the following video, senior biotech specialist Brian Orelli and health-care bureau chief Max Macaluso discuss the implications. While it could mean that biotechs have trouble getting a second drug approved, it's likely that many of them got acquired before they had the chance. GlaxoSmithKline (GSK -0.83%), for instance, bought its partner Human Genome Sciences after it got its lupus drug approved. And Celgene (CELG) bought Abraxis for its cancer drug Abraxane before the biotech could use its platform to get additional drugs approved.

Looking at the current crop of one-drug wonders, Medivation (MDVN) is an attractive company whether it continues alone or gets acquired by its partner Astellas Pharma. Watch the following video for more of Brian's and Max's thoughts on Medivation.