Although we don't believe in timing the market or panicking over market movements, we do like to keep an eye on big changes -- just in case they're material to our investing thesis.
What: Shares of Dendreon (NASDAQ:DNDN), a biotech company that utilizes immunotherapeutic vaccines to treat cancer, soared as much as 14% after reporting additional data on Provenge, its advanced prostate cancer vaccine, at the American Urological Association's annual meeting.
So what: According to Dendreon's press release, while no specific figures were mention, it did note that data collected from its ProACT and IMPACT studies suggest that "Provenge elicits an immune response associated with an overall survival benefit." Dendreon's presentation also includes data from its PROCEED trial which suggests similar treatment patterns for urologists and oncologists for Provenge patients with metastatic castration-resistant prostate cancer. As chief medical officer Andrew Sandler, M.D., noted, "The elevated immune response against prostate-specific antigen in the ProACT and IMPACT studies is correlated with overall survival, and may point to a useful biomarker of treatment benefit."
Now what: The data surrounding Provenge has never been much of a question mark. In essence, we knew that it provided a marked treatment benefit over the placebo in studies. The problem has been Dendreon's inability to capitalize on its product, allowing competitors to easily gain the upper hand within the space. Whether it's Dendreon's lack of a marketing partner, its inexperienced sales force, or the fact that Provenge's $93,000 price tag scares physicians and patients away, or a combination of all three for that matter, the point is that Dendreon's inability to turn a profit could put its long-term survival in question. Dendreon does have additional clinical research under way, but following two restructurings which have included hefty job cuts it doesn't look like the company is still anywhere near profitability on Provenge alone. Until we see Dendreon make significant progress with improving Provenge sales I'd strong suggest keeping your distance.
Dendreon may have soared today, but it'll likely take a backseat to this top stock over the long run
Give me five minutes and I'll show how you could own the best stock for 2014. Every year, The Motley Fool's chief investment officer hand-picks 1 stock with outstanding potential. But it's not just any run-of-the-mill company. It's a stock perfectly positioned to cash in on one of the upcoming year's most lucrative trends. Last year his pick skyrocketed 134%. And previous top picks have gained upwards of 908%, 1,252% and 1,303% over the subsequent years! Believe me, you don't want to miss what could be his biggest winner yet! Just click here to download your free copy of "The Motley Fool's Top Stock for 2014" today.
Sean Williams has no material interest in any companies mentioned in this article. You can follow him on CAPS under the screen name TMFUltraLong, track every pick he makes under the screen name TrackUltraLong, and check him out on Twitter, where he goes by the handle @TMFUltraLong.
Try any of our Foolish newsletter services free for 30 days. We Fools may not all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors. The Motley Fool has a disclosure policy.