In the spirit of World Cup competition, we're holding our own tournament in search of the Better Stock Today. We're pitting 32 companies against each other and you, the reader, will determine the winner.

Isis Pharmaceuticals (NASDAQ: ISIS) takes on LINN Energy (NASDAQ: LINE) for this first round-robin match up in our search for the better stock today.

David Williamson, Motley Fool health care analyst, thinks Isis should advance to the next round because of one big reason -- its amazing drug pipeline. Wall Street heralds it as the best in biotech and puts Isis in play as a takeover target. A virtual who's who of big pharma has struck partnership deals. Isis already has orphan drug Kynamro on the market, and has seen recent success from a mid-stage study for an anti-clotting drug. A recent sell-off has given investors a chance to get this deep pipeline at a discounted price.

Joel South, energy analyst at The Motley Fool, thinks LINN Energy is the premier upstream MLP and worth of your investment. LINN offers a top tier distribution yield of 9.7% and management continues to execute on its strategy of acquiring mature oil and gas assets that are operated strategically to increase cash flows and return excess cash to unitholders.  

Vote here to determine the winner of this match and sound off in the comments. Check back to Fool.com to see who advances in the tournament.