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5

Icahn's Smiling -- Should We Be?

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Biogen Idec's (Nasdaq: BIIB  ) fourth quarter results must have made Carl Icahn smile. But the guidance for next year gives me pause.

Let's recap: Revenue was up just 5%, while adjusted EPS were up a 29% thanks to cost cutting measures. Next year's guidance was more of the same: Revenue growth is expected to be in the "mid single digits," but growth in adjusted EPS is expected to top 10%.

While keeping cost of goods and SG&A expenses in check is undoubtedly a good thing, there's one number in the company's guidance that should have long-term investors a little worried.

Metric

2005

2006

2007

2008

2009

2010 Estimate

Percent of Revenue Spent on R&D

30.9%

26.8%

29.2%

26.2%

29.3%

24%-27%

Source: Capital IQ, a division of Standard & Poor's and company press release.

The low end of Biogen's guidance is well below the company's average over the last several years. Some of the decreased spending probably has to do with a few drugs that haven't worked out. Biogen killed two blood-cancer drugs last October, and announced yesterday that it wouldn't develop heart-failure drug Adentri. The latter isn't a big shock, given Merck's (NYSE: MRK  ) failure of a similar drug.

Saving money now will line investors' pockets, but at what cost to future earnings? This is a drug company, folks, one that needs healthy R&D spending in order to grow in the future.

In addition, earnings growth from existing drugs might not come so easily pretty soon. Novartis (NYSE: NVS  ) and Merck KGaA are both developing oral drugs to treat multiple sclerosis. Assuming those get approved, they probably won't affect sales of Biogen's and Elan's (NYSE: ELN  ) Tysabri too much, because it's often used after other drugs fail.

But those oral drugs could cut into sales of MS drugs that have to be injected, like Biogen's own Avonex, which made up more than 70% of the company's product revenue last year. Competing drugs like Teva Pharmaceutical's (Nasdaq: TEVA  ) Copaxone and Rebif from Pfizer (NYSE: PFE  ) and EMD Serono would also be affected, but that's not my worry.

Biogen's best strategy at this point is to use some of its $1.3 billion in cash and equivalents to license late-stage drug candidates, like it did with Acorda Therapeutics' (Nasdaq: ACOR  ) Ampyra. Boosting the pipeline -- and the R&D spending in the process -- is the only way Biogen can get back to the double-digit revenue growth that investors have grown accustomed to ... and which the company needs in order to sustain those double-digit earnings growth targets.

Chuck Saletta wants to know whether this guy is the next Buffett. Hint: He doesn't mean Icahn. 

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Pfizer is a Motley Fool Inside Value pick. Elan is a Rule Breakers selection. Novartis is a Global Gains recommendation. Try any of our Foolish newsletters today, free for 30 days.

Fool contributor Brian Orelli, Ph.D., doesn't own shares of any company mentioned in this article. The Fool's disclosure policy is willing to spend a buck to make two down the line.


Comments from our Foolish Readers

Help us keep this a respectfully Foolish area! This is a place for our readers to discuss, debate, and learn more about the Foolish investing topic you read about above. Help us keep it clean and safe. If you believe a comment is abusive or otherwise violates our Fool's Rules, please report it via the Report this Comment Report this Comment icon found on every comment.

  • Report this Comment On February 10, 2010, at 11:56 AM, tecmo wrote:

    I am not sure I see the trend that you are.

    2005: 30.9%

    2006: 26.8% <- -4.1%

    2007: 29.2% <- +2.4%

    2008: 26.2% <- -3.0%

    2009: 29.3% <- +3.1%

    2010 is then presented as a range of 24% to 27%; its not unlikely that it will come in around 26% which would put in on par with 2006 & 2008 numbers. It is a bit strange that the numbers oscalate between 29-30 in odd years and 26-27 in even years; but 2010 is just a continuation of that trend.

    I don't see any reason to panic with the 2010 R&D expenditure forecasts. I will agree that Biogen needs to put the 1.3B of cash to work. It represents nearly 10% of its market cap and it should be put to use developing and marketing new drugs.

  • Report this Comment On February 10, 2010, at 11:57 AM, tecmo wrote:

  • Report this Comment On February 10, 2010, at 5:42 PM, TMFBiologyFool wrote:

    The numbers weren't there to show a trend downward, so much as the average spending. I agree that if it comes in at 26%-27% there isn't much to worry about. But 24% should give investors that plan to hold for many years a reason to second guess themselves although they might want to wait and see what 2011 looked like.

    -Brian

  • Report this Comment On February 11, 2010, at 10:34 AM, mgw6 wrote:

    Big Pharma has demonstrated that increased spending does not increase R & D productivity or the probability for delivering the innovation the healthcare market expects today. Look at the billions spent on R & D over the past decade when Pharma kept increasing investment (looks impressive and sounds impressive) but with little to show for now.

    Evaluating the appropriate level of R & D spend requires a closer look at the expertise and focus of discovery research (are they looking at diseases with commercial potential and do they have the expertise and resources to succeed?) and whether the products in late stage are worth the level of spend. A few well funded high probability programs is better than spending more on a lot of programs just to keep the spend up and investors and analysts happy. Just because the cash is there doesn't mean it should be spent.

    I do agree that if the internal projects are not worth the investment (few companies will admit this because few investors want to see this), companies must get aggressive about in-licensing.

    Mike Wokasch

    www.pharmareform.com

  • Report this Comment On February 11, 2010, at 11:05 AM, mgw6 wrote:

    Big Pharma has demonstrated that increased spending does not increase R & D productivity or the probability for delivering the innovation the healthcare market expects today. Look at the billions spent on R & D over the past decade when Pharma kept increasing investment (looks impressive and sounds impressive) but with little to show for now.

    Evaluating the appropriate level of R & D spend requires a closer look at the expertise and focus of discovery research (are they looking at diseases with commercial potential and do they have the expertise and resources to succeed?) and whether the products in late stage are worth the level of spend. A few well funded high probability programs is better than spending more on a lot of programs just to keep the spend up and investors and analysts happy. Just because the cash is there doesn't mean it should be spent.

    I do agree that if the internal projects are not worth the investment (few companies will admit this because few investors want to see this), companies must get aggressive about in-licensing.

    Mike Wokasch

    www.pharmareform.com

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2/9/2012 4:00 PM
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