LONDON -- Shares in pharmaceuticals play Shire (SHP) (NASDAQ: SHPG) have endured a turbulent start to 2013, collapsing 8.8% from February's near-one-year high around 2,150 pence after takeover speculation had earlier propelled stocks higher.

Despite this recent weakness, I believe that stock in the pharmaceuticals giant should head skywards again as galloping R&D work, combined with the likelihood of busy acquisition activity, drives growth in coming years. Goldman Sachs affirmed its 2,675 pence share price target just this month, representing 36% upside from current levels.

Stunning growth potential to drive sales
I believe that the firm's prolific research and development activity should deliver solid revenue growth over the long term. Shire spent $848.8 million on this area last year, a 16% annual rise, which should boost its pipeline and deliver excellent sales further out. Indeed, Goldman Sachs expects revenues to grow around 10% through to 2017 versus a 3% rise across the entire pharma sector.

And Shire's sterling record of innovation should be underpinned by M&A activity in coming years as it puts its $1.4 billion cash pile to work. Shire acquired SARCode Bioscience just last month to boost its opthalmology business -- the U.S. firm's phase 3 compound Lifitegrast product is being tested for dry eye disease. The move follows the purchase of Sweden's Premacure AB in February, which is currently in phase 2 testing for the prevention of eye disorder retinopathy of prematurity, or ROP.

Earnings explosion predicted for 2013
City forecasters expect earnings per share to snap 68% higher in 2013, following last year's 14% decline, with a rise to 147 pence penciled in. These are then expected to advance 14% in 2014 to 168 pence.

The company currently changes hands on a P/E rating of 13.5 and 11.9 for 2013 and 2014, respectively, providing a bloated discount to a forward earnings multiple of 39.7 for the broad pharmaceuticals and biotechnology sector. And Shire's position as a true value stock is underlined by a low price/earnings to growth, or PEG, rating of 0.2 and 0.8 for this year and next -- a reading below 1 is considered excellent value for money.

Despite Shire's recent buyback program -- the firm commenced a $500 million purchase scheme late last year -- the stock does not provide an attractive pick for income investors, with dividend yields of just 0.6% and 0.7% predicted for this year and next below the wider sector's average 2.4% payout.

However, in my opinion Shire's decision to allocate its meaty cash pile toward developing future growth makes it an exciting pick, with revenues ready to balloon in coming years.

The canny guide for clever investors
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