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Market Data Table

Breakfast News: Soleno Soars 30% on Buyout Talk

April 6, 2026

Thursday's Markets
S&P 500 6,583 (+0.11%)
Nasdaq 21,879 (+0.18%)
Dow 46,505 (-0.13%)
Bitcoin $66,955 (-1.57%)

Chart showing Neurocrine's and Soleno's stock prices over the past three years, with Neurocrine currently sitting at $132 and Soleno at $39.

1) Neurocrine Lines Up Soleno Acquisition

Neurocrine Biosciences (NASDAQ:NBIX) -- recommended in Stock Advisor by Team Rule Breakers -- is close to acquiring Soleno Therapeutics (NASDAQ:SLNO), says the Financial Times. The deal, reportedly for over $2.5 billion, could value Soleno above $50 per share. The stock jumped more than 30% overnight after the price had been climbing since the end of March. Neurocrine dipped around 1%.

Genetic obesity: Soleno makes the first commercial treatment for extreme hunger -- a condition known as hyperphagia -- caused by Prader-Willi syndrome, a genetic disorder affecting sufferers from childhood.
Breakthrough fourth quarter: Soleno reported a Q4 profit in February after its new Prader-Willi treatment became its first approved medicine and reached rapid profitability.

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2) Markets Rebound Last Week

Markets reversed their recent downtrend in a trading week shortened by the Good Friday close, as the S&P 500 gained 3.4% and the Nasdaq 4.4%. Confidence was boosted by Friday's jobs report showing 178,000 jobs added in March -- ahead of estimates for 60,000 and reversing February's loss of 92,000. S&P 500 futures pushed above 0.4% pre-market, as Nasdaq futures gained over 0.7%.

Key inflation prints: The March consumer price index due Friday is expected to show inflation creeping up following the Iran war, predicted at 3.3% year over year, ahead of the previous month's 2.4%. It follows Thursday's Personal Consumption Expenditures (PCE) update for February, expected to be largely flat.
What's next for the Fed?: Core PCE is the Federal Reserve's preferred index, as it excludes short-term food and fuel changes. With hopes of an April rate cut vanishing, the CME FedWatch tool shows a 99.5% chance of no change, with the other 0.5% predicting a rise.

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3) Coinbase Pursues National Trust Company Charter

Cryptocurrency platform Coinbase (NASDAQ:COIN) says it has conditional approval to establish a national trust bank. Should further examination steps progress to full approval, the Coinbase National Trust Company could handle federally regulated crypto custody and services.

"Seeking the benefits of a U.S. bank charter without satisfying the full scope of U.S. bank regulations": The Independent Community Bankers of America called the decision a "grave mistake." Coinbase Co-CEO Greg Tusar, meanwhile, assured us, "Coinbase is not becoming a commercial bank. We will not be taking retail deposits. We will not be engaging in fractional reserve banking."
Bitcoin-Backed Mortgages: Fool analyst Alicia Alfiere recently explained how Coinbase is joining up with Better Mortgage (NASDAQ:BETR) to offer a mortgage using Bitcoin (CRYPTO:BTC) as collateral for an additional loan instead of a deposit. "This feels similar to the old practice of using one loan to cover 80% of the house and another to cover 20%," Alicia said.

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4) Key Foolish Earnings to Watch

RPM (NYSE:RPM) is set to report Q3 on Wednesday, after the Dividend Investor rec posted a 14% fall in earnings per share (EPS) in its previous quarter. Management predicted sales and adjusted EBIT (earnings before interest and taxes) gains in the current quarter, following cost-saving measures. There's a 2.2% full-year dividend forecast.
Constellation Brands (NYSE:STZ) should give us a feel for how inflation is hitting consumers the same day, with Q4 and full-year results due. The beer, wine, and spirits retailer beat revenue estimates in the previous quarter.
Delta (NYSE:DAL) also reports on Wednesday and should provide insight into escalating airline costs following the attacks on Iran. Fool analyst Bill Barker has pointed out, "Despite the fuel costs, Delta is not running the Mid East as a hub," so it might not suffer as badly as some.

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5) Your Take

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