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Vertex Pharmaceuticals(NASDAQ) VRTX

Market Cap$130.67BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.
Since IPO (1991)+11,357%
5 Year+165%
1 Year+31%
1 Month+6%
$528.08
+2.43%
+12.53Today
After hours$529.69+$1.61 (+0.31%)
Vertex Pharmaceuticals last closing stock price
MetricPriceDate
Last closeUSD 515.552026-08-17
Vertex Pharmaceuticals stock price return by period
PeriodPrice returnPrice at period startPeriod start date
1 week-1.6%USD 523.912026-08-10
1 month+6.16%USD 485.652026-07-17
3 month+18.71%USD 434.312026-05-19
Year to date+13.72%USD 453.362025-12-31
1 year+31.25%USD 392.792025-08-15
3 year+49.51%USD 344.822023-08-18
5 year+164.7%USD 194.772021-08-18
Since inception+11,356.67%USD 4.501991-07-24

Vertex Pharmaceuticals Financials at a Glance

Market Cap

$130.67BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

Revenue (TTM)

$12.62B

Net Income (TTM)

$4.41B

EPS (TTM)

$17.19

P/E Ratio

29.99

Dividend

$0.00

Beta (Volatility)

0.57 (Low)

Price

$528.08

Volume

1,497,081.225

Open

$520.00

Previous Close

$528.19

Daily Range

$517.34 - $533.78

52-Week Range

$374.17 - $546.17

Estimated Earnings Date

Nov 2, 2026

VRTX News

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Vertex Pharmaceuticals Just Hit an All-Time High. Here's Why the Biotech Stock Could Soar Even More

Prosper Junior BakinyAug 14, 2026
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5 Best CRISPR Gene Editing ETFs for 2026 and How to Invest

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Biotech vs. Pharma: What's the Difference?

Keith SpeightsAug 12, 2026
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Could 1 Tiny Biotech Topple Vertex Pharmaceuticals' Cystic Fibrosis Empire?

Prosper Junior BakinyAug 7, 2026
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Why Vertex Pharmaceuticals Stock Ticked Higher on Tuesday

Eric VolkmanAug 4, 2026
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Vertex Pharmaceuticals Just Made a $10 Billion Acquisition Worth Watching

Prosper Junior BakinyJul 19, 2026
Page 1

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About Vertex Pharmaceuticals

Vertex Pharmaceuticals Incorporated treats people with life-threatening genetic diseases. These medicines help patients manage cystic fibrosis and blood disorders. The company also develops new ways to treat severe pain.

Medicines for Rare Conditions

  • Cystic Fibrosis Treatments: Therapies like TRIKAFTA and ALYFTREK that treat genetic lung disease; generated $3.2 billion in the second quarter of 2026.
  • Genetic Blood Therapies: CASGEVY uses gene editing to treat sickle cell disease and beta thalassemia; recorded $76.4 million in the second quarter of 2026.
  • Acute Pain Management: JOURNAVX is an approved medicine for moderate-to-severe acute pain; produced $49.6 million in the second quarter of 2026.

Expanding Beyond Cystic Fibrosis

  • Agreed to acquire Crinetics Pharmaceuticals in July 2026 for approximately $10.0 billion to expand into endocrine disease treatments.
  • Acquired Alpine Immune Sciences and its lead molecule, povetacicept, for $5.0 billion in 2024 to target autoimmune diseases.
  • Partnered with Zai Lab and Ono Pharmaceuticals in 2025 to develop and sell povetacicept in Asian markets.
  • Secured reimbursement for ALYFTREK in four additional countries, including Spain, during the second quarter of 2026.

Specialized Science and Global Reach

Vertex operates a specialized global network to manufacture and distribute complex biological and cell therapies. The company maintains a high level of research investment to create first-in-class treatments for diseases with significant unmet needs.

Financial Performance in 2026

  • Total revenues rose to $3.3 billion in the second quarter of 2026, up 12% year over year.
  • Selling, general, and administrative expenses reached $582.2 million in the second quarter of 2026, up 37% year over year.
  • Cash, cash equivalents, and marketable securities totaled $13.6 billion as of June 30, 2026.
  • Market capitalization reached $126.1 billion in the second quarter of 2026, up 10.4% year over year.
  • Research and development expenses totaled $993.8 million in the second quarter of 2026, up 2% year over year.

A Changing Biotechnology Leader

Vertex has evolved from a cystic fibrosis specialist into a multi-disease biotechnology leader. Its expansion into gene editing and pain management diversification strengthens its long-term commercial profile.

AI Generated • Aug 5, 2026

Industry

Biotechnology

Sector

Health Care

Employees

6,400

CEO

Reshma Kewalramani, MD

Website

www.vrtx.com

Headquarters

Boston, MA 02210, US

VRTX Financials

Key Financial Metrics (TTM)

Gross Margin

86.04%

Operating Margin

38.59%

Net Income Margin

34.89%

Return on Equity

23.31%

Return on Capital

21.11%

Return on Assets

16.06%

Earnings Yield

3.33%

Dividend Yield

0.00%

Payout Ratio

0.00%

Stock Overview

Market Cap

$130.67BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

Shares Outstanding

253.46M

Volume

1.50M

Avg. Volume

1.56M

Financials (TTM)

Gross Profit

$10.86B

Operating Income

$4.87B

EBITDA

$5.44B

Operating Cash Flow

$4.29B

Capital Expenditure

-$496.80M

Free Cash Flow

$3.80B

Cash & ST Invst.

$7.85B

Total Debt

$1.98B

Vertex Pharmaceuticals Performance Analysis

Vertex Pharmaceuticals annual revenue and year-over-year revenue growth by fiscal year
Fiscal yearPeriod endRevenueYoY growth
20222022-12-31USD 8,748,200,00015.0%
20232023-12-31USD 9,839,000,00012.5%
20242024-12-31USD 10,984,400,00011.6%
20252025-12-31USD 12,074,600,0009.9%
Vertex Pharmaceuticals sequential (quarter-over-quarter) revenue growth by fiscal quarter
Fiscal quarterPeriod endQoQ growth
Q32025-09-303.8%
Q42025-12-314.9%
Q12026-03-31-7.4%
Q22026-06-3011.6%
Vertex Pharmaceuticals annual diluted earnings per share and year-over-year EPS growth by fiscal year
Fiscal yearPeriod endDiluted EPSYoY growth
20222022-12-31USD 12.8242.3%
20232023-12-31USD 13.898.4%
20242024-12-31USD -2.08N/A
20252025-12-31USD 15.32N/A
Vertex Pharmaceuticals sequential (quarter-over-quarter) diluted earnings per share growth by fiscal quarter
Fiscal quarterPeriod endQoQ growth
Q32025-09-305.3%
Q42025-12-3110.7%
Q12026-03-31-13.5%
Q22026-06-307.2%

Revenue Growth Rate

Annual and quarterly growth comparison

Earnings Per Share Growth Rate

Annual and quarterly EPS growth comparison

Quarterly Performance

Name
Q2 2026YOY CHG

Revenue

$3.33B

+12.5%

Gross Profit

$2.84B

+11.2%

Gross Margin

85.33%

N/A

Market Cap

$130.67BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

N/A

Market Cap/Employee

$20.42M

N/A

Employees

6,400

N/A

Net Income

$1.10B

+6.5%

EBITDA

$1.39B

+4.0%

Quarterly Fundamentals

Name
Q2 2026YOY CHG

Total Cash

$7.85B

+23.0%

Total Debt

$1.98B

+29.5%

Accounts Receivable

$2.13B

+12.7%

Inventory

$1.77B

+17.7%

Long Term Debt

$1.98B

+29.5%

Short Term Debt

$0.00

N/A

Return on Assets

16.06%

N/A

Return on Invested Capital

20.74%

N/A

Free Cash Flow

$1.01B

+9.3%

Operating Cash Flow

$1.13B

+4.9%

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Questions About VRTX

What is the current price of Vertex Pharmaceuticals?

Vertex Pharmaceuticals is trading at $528.19 per share.

What is the 52-week range for Vertex Pharmaceuticals?

Over the past 52 weeks, Vertex Pharmaceuticals has traded between $374.17 and $546.17.

How much debt does Vertex Pharmaceuticals have?

As of the most recent reporting period, Vertex Pharmaceuticals reported total debt of $1.98B.

How much cash does Vertex Pharmaceuticals have on hand?

Vertex Pharmaceuticals reported $6.15B in cash and cash equivalents in its most recent financial results.

What is Vertex Pharmaceuticals’s dividend yield?

Vertex Pharmaceuticals does not currently have a dividend yield.

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