Why Sangamo Biosciences, Inc. Trounced the Market

Sangamo Biosciences shot up 20% today, but this may still be one to watch at a distance.

Mar 6, 2014 at 7:38PM

Shares of Sangamo Biosciences (NASDAQ:SGMO) are up more than 20% today on the news that HIV patients who were given Bristol-Myers Squibb's (NYSE:BMY) drug Cytoxan responded better to Sangamo's drug SB-728-T, which is made up of the patient's own genetically modified cells.

However, in this video, Motley Fool health-care analyst David Williamson points to a few things that investors need to keep in mind that should temper some of the enthusiasm. Firstly, the success story here was only two patients, and secondly, with Sangamo's drug, the virus is stabilized, but still detectable. Comparing this against current anti-viral drugs, which bring the virus down to undetectable levels, means Sangamo will still need to do better if it wants patients to switch. David takes a close look at the company in this video, discusses its financial situation, and points to some key trials coming up that will give investors a much better idea whether they should be jumping in on this stock.

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David Williamson has no position in any stocks mentioned. The Motley Fool has no position in any of the stocks mentioned. Try any of our Foolish newsletter services free for 30 days. We Fools may not all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors. The Motley Fool has a disclosure policy.

A Financial Plan on an Index Card

Keeping it simple.

Aug 7, 2015 at 11:26AM

Two years ago, University of Chicago professor Harold Pollack wrote his entire financial plan on an index card.

It blew up. People loved the idea. Financial advice is often intentionally complicated. Obscurity lets advisors charge higher fees. But the most important parts are painfully simple. Here's how Pollack put it:

The card came out of chat I had regarding what I view as the financial industry's basic dilemma: The best investment advice fits on an index card. A commenter asked for the actual index card. Although I was originally speaking in metaphor, I grabbed a pen and one of my daughter's note cards, scribbled this out in maybe three minutes, snapped a picture with my iPhone, and the rest was history.

More advisors and investors caught onto the idea and started writing their own financial plans on a single index card.

I love the exercise, because it makes you think about what's important and forces you to be succinct.

So, here's my index-card financial plan:


Everything else is details. 

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