These Sales Matter Most

Human Genome Sciences (Nasdaq: HGSI  ) is trading down about 5% today as the Dow Jones (INDEX: ^DJI) sits in the green after an analyst from Citi said HGS and GlaxoSmithKline's (NYSE: GSK  ) new lupus drug, Benlysta, is getting a “lukewarm” welcome from doctors.

Earlier this month Dendreon (Nasdaq: DNDN  ) fell 65% after management announced that its sales ramp for Provenge would be substantially flatter than expected. The new guidance is for "modest" quarter-over-quarter revenue growth.

But the thing is, the sales ramp -- how quickly sales increase -- is fairly meaningless for the long-term investor. Sure, bringing in revenue quickly and producing positive cash flow is important for biotechs launching their first drugs. But, assuming you're going to hold your shares for many years, the value of the biotech is based on what you think sales will look like at that point: the peak sales for the drug.

The question investors have to ask themselves is whether the relatively slow starts are a sign that peak sales might be lower. Are doctors just not prescribing it right now or will they not prescribe it at all?

Benlysta treats lupus, a disease that waxes and wanes. While the symptoms aren't pleasant, the disease isn't immediately life-threatening either. Doctors may put a few patients on the drug, see how they do, and then increase their prescribing habits as they gain confidence with the drug. AVANIR Pharmaceuticals' (Nasdaq: AVNR  ) Nuedexta has run into the same problem.

For Provenge, it's possible that doctors aren't prescribing the prostate cancer treatment because they don't think it works or isn't worth the money, which would obviously affect peak sales. But the company's explanation that doctors are worried about having to buy the drug with the possibility of not being reimbursed seems completely reasonable. If that's the problem, once doctors are convinced insurance companies and Medicare will pay quickly, they'll increase their prescriptions and peak sales shouldn't be affected.

For both Benlysta and Provenge, the truth probably lies somewhere in the middle. The companies should be able to recover from slow starts; both are innovative medications. But the lack of enthusiasm, compared to a drug like Vertex Pharmaceuticals' (Nasdaq: VRTX  ) Incivek that took off out of the gates, could mean that peak sales might be slightly lower and/or take longer to reach.

Keep track of Human Genome Sciences and Dendreon as they launch their drugs. Just click on the companies' names to add them to My Watchlist, the Fool's free watchlist service.

Fool contributor Brian Orelli holds no position in any company mentioned. Click here to see his holdings and a short bio. The Motley Fool owns shares of Dendreon and GlaxoSmithKline. Motley Fool newsletter services have recommended buying shares of GlaxoSmithKline and Vertex Pharmaceuticals. Try any of our Foolish newsletter services free for 30 days. We Fools may not all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors. The Motley Fool has a disclosure policy.


Read/Post Comments (1) | Recommend This Article (5)

Comments from our Foolish Readers

Help us keep this a respectfully Foolish area! This is a place for our readers to discuss, debate, and learn more about the Foolish investing topic you read about above. Help us keep it clean and safe. If you believe a comment is abusive or otherwise violates our Fool's Rules, please report it via the Report this Comment Report this Comment icon found on every comment.

Add your comment.

Sponsored Links

Leaked: Apple's Next Smart Device
(Warning, it may shock you)
The secret is out... experts are predicting 458 million of these types of devices will be sold per year. 1 hyper-growth company stands to rake in maximum profit - and it's NOT Apple. Show me Apple's new smart gizmo!

DocumentId: 1547093, ~/Articles/ArticleHandler.aspx, 8/30/2014 2:38:19 PM

Report This Comment

Use this area to report a comment that you believe is in violation of the community guidelines. Our team will review the entry and take any appropriate action.

Sending report...


Advertisement