When transplants are performed, patients have to take drugs to suppress the immune system, keeping it from rejecting the new cells it sees as foreign. Unfortunately, the suppression can also leave patients vulnerable to attacks from routine viruses (such as cytomegalovirus) that the immune system usually handles easily.
To control the cytomegalovirus, Vical
Total payments of $130 million aren't really all that much for a phase-3-ready compound; consider that Micromet's
While the vaccine will have a much smaller market than vaccines like Pfizer's
Of course, talk of sales and royalties is a little premature at this point. TransVax needs to prove successful in its yet-to-be-started phase 3 trial before we can transplant those milestone and royalty payments to the revenue line.
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