Please ensure Javascript is enabled for purposes of website accessibility

Is This Why AnaptysBio Inc. Fell on Monday?

By Cory Renauer – Apr 2, 2018 at 6:52PM

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More

It looks like investors are still arguing about last week's peanut allergy results.

What happened

Shares of AnaptysBio Inc. (ANAB -3.50%), a clinical-stage biotech developing therapeutic antibodies, slipped 13.1% in late-day trading and finished Monday's session 9.7% lower. The company has been quiet since announcing data from a recent peanut allergy trial that has been the source of some disagreement. It appears that a second look at the interim data from the mid-stage trial with ANB020 put a bad taste in shareholders' mouths this afternoon.

So what 

AnaptysBio has four partnered drugs in clinical trials and two more that the company owns outright. ANB020 is the wholly-owned candidate furthest along the development timeline. The stock marched up to an all-time high following data from a mid-stage eczema trial released in February but has fallen about 15% since releasing spotty data from a small peanut allergy trial.

Chalkboard with a drawing of a downward sloping chart.

Image source: Getty Images.

Investigators gave ANB020 to 13 adults with moderate to severe peanut allergy symptoms and then essentially made them eat some peanuts a couple weeks later. Six of the 13 showed an improved peanut tolerance, which might be pretty good. There weren't any improvements in peanut tolerance among patients randomized to receive a placebo, but zero out of three isn't a lot to go on.

Now what

While the results warrant further investigation, they failed to impress analysts bullish for potential competitors in the peanut allergy space. The most fearsome source of competition could come from Aimmune Therapeutics Inc. (AIMT) and its lead candidate AR101. During a pivotal study that wrapped up recently, 96% of patients who completed treatment were able to tolerate a 300 mg dose of peanut, while 63% could handle a whole 1,000 mg of peanut protein.

Aimmune's candidate put up arguably better data, but the pivotal study was limited to children between the ages of 4 and 17, while AnaptysBio has its lead candidate aimed at an adult population. If you're still worried about Aimmune's candidate in the peanut allergy space, remember ANB020's main source of value is as a treatment for eczema. 

Cory Renauer has no position in any of the stocks mentioned. The Motley Fool recommends AnaptysBio. The Motley Fool has a disclosure policy.

Invest Smarter with The Motley Fool

Join Over 1 Million Premium Members Receiving…

  • New Stock Picks Each Month
  • Detailed Analysis of Companies
  • Model Portfolios
  • Live Streaming During Market Hours
  • And Much More
Get Started Now

Stocks Mentioned

AnaptysBio Stock Quote
$24.52 (-3.50%) $0.89
Aimmune Therapeutics, Inc. Stock Quote
Aimmune Therapeutics, Inc.

*Average returns of all recommendations since inception. Cost basis and return based on previous market day close.

Related Articles

Motley Fool Returns

Motley Fool Stock Advisor

Market-beating stocks from our award-winning analyst team.

Stock Advisor Returns
S&P 500 Returns

Calculated by average return of all stock recommendations since inception of the Stock Advisor service in February of 2002. Returns as of 09/27/2022.

Discounted offers are only available to new members. Stock Advisor list price is $199 per year.

Premium Investing Services

Invest better with The Motley Fool. Get stock recommendations, portfolio guidance, and more from The Motley Fool's premium services.