The following video is from Wednesday's edition of Investor Beat, in which host Chris Hill and Motley Fool analysts Jason Moser and Matt Argersinger dissect the hardest-hitting investing stories of the day.

Shares of MAKO Surgical (UNKNOWN:UNKNOWN) skyrocketed on news that Stryker (NYSE:SYK) will acquire the company for $1.65 billion in cash. AutoZone (NYSE:AZO) shares were bolstered slightly by news that fourth-quarter profits rose 15%. J.C. Penney (NYSE:JCP) hits a 13-year low on news of a Goldman Sachs downgrade. And Chinese online media company SINA (NASDAQ:SINA) continues its rise, now up more than 60% YTD. In this segment, Matt and Jason look at four stocks making big moves today.

Chris Hill and Matthew Argersinger have no position in any stocks mentioned. Jason Moser owns shares of SiINA. The Motley Fool recommends Goldman Sachs, MAKO Surgical, and SINA and owns shares of SINA. Try any of our Foolish newsletter services free for 30 days. We Fools don't all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors. The Motley Fool has a disclosure policy.