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Jade Biosciences(NASDAQ) JBIO

Current Price$20.02
Market Cap$1.22BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.
Since IPO (2025)+98%
5 Year-61%
1 Year+141%
1 Month-8%
Jade Biosciences last closing stock price
MetricPriceDate
Last closeUSD 20.082026-07-24
Jade Biosciences stock price return by period
PeriodPrice returnPrice at period startPeriod start date
1 week-3.74%USD 20.862026-07-17
1 month-8.31%USD 21.902026-06-24
3 month-19.62%USD 24.982026-04-24
Year to date+30.14%USD 15.432025-12-31
1 year+141.06%USD 8.332025-07-24
3 year-66.88%USD 60.632023-07-25
5 year-61.41%USD 52.042021-07-23
Since inception+98.03%USD 10.142025-04-29

Jade Biosciences Financials at a Glance

Market Cap

$1.22BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

Revenue (TTM)

$0.00

Net Income (TTM)

-$129.61M

EPS (TTM)

-$2.99

P/E Ratio

-6.72

Dividend

$0.00

Beta (Volatility)

0.16 (Low)

Price

$20.02

Volume

15,792

Open

$19.64

Previous Close

$20.02

Daily Range

$19.05 - $20.08

52-Week Range

$6.67 - $28.00

Estimated Earnings Date

Aug 12, 2026

JBIO News

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About Jade Biosciences

Jade makes new medicines for people whose immune systems attack their own bodies. These treatments help patients with serious kidney problems and other long-term health issues. The company aims to make drugs that are easier to use and more effective than current options.

What is Jade Building?

  • JADE101: A monoclonal antibody (mAb), or lab-made protein, designed to treat IgA nephropathy (IgAN), a chronic kidney disease. It targets the APRIL protein to stop harmful antibody production.
  • JADE201: An experimental treatment for rheumatoid arthritis and other autoimmune disorders. This drug targets the BAFF-R receptor to clear out harmful B cells from the immune system.
  • JADE301: A preclinical program focused on a specific, undisclosed biological pathway to expand the company's treatment portfolio.

Alliances and Agreements

  • Entered into a research agreement with Paragon Therapeutics, Inc. in July 2024 to discover and develop new antibody treatments.
  • Secured exclusive worldwide licenses from Paragon Therapeutics, Inc. for JADE101 in October 2024 and JADE201 in October 2025.
  • Partnered with WuXi Biologics and Patheon Biologics LLC in early 2025 to handle the manufacturing and testing of its drug candidates.
  • Launched its first human clinical trial for JADE101 in August 2025, marking the company's shift into a clinical-stage business.

What Makes Their Science Different

Jade uses half-life extension technology to make its treatments last longer in a patient's body. This approach allows for less frequent injections, making it more convenient for people with chronic illnesses to manage their health.

A Look at the Numbers

  • Revenue remained at zero for the fiscal year ended December 31, 2025, as products are still in development.
  • Operating income was -$35 million in Q4 2025, a loss that worsened by 446.3% from -$6.4 million in Q4 2024.
  • Net income reached -$67.6 million in Q4 2025, declining 1144.6% from a loss of -$5.4 million in the previous year.
  • Market capitalization grew to $1.1 billion in Q4 2025, representing a 1322% increase from $76.8 million in Q4 2024.
  • Operating cash flow was -$33.6 million in Q4 2025, which worsened by 204.6% compared to the -$11 million reported in Q4 2024.

The Road Ahead

Jade has evolved from a discovery-focused startup into a clinical-stage biotech firm. Its future depends on the clinical trial results of its licensed antibody programs for autoimmune diseases.

AI Generated • May 1, 2026

Industry

Biotechnology

Employees

55

CEO

Tom Frohlich, MBA

Headquarters

Waltham, MA 02453, US

JBIO Financials

Key Financial Metrics (TTM)

Gross Margin

0.00%

Operating Margin

0.00%

Net Income Margin

0.00%

Return on Equity

-51.34%

Return on Capital

-34.07%

Return on Assets

-40.57%

Earnings Yield

-14.88%

Dividend Yield

0.00%

Payout Ratio

0.00%

Stock Overview

Market Cap

$1.22BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

Shares Outstanding

60.86M

Volume

15.79K

Avg. Volume

1.04M

Financials (TTM)

Gross Profit

-$9.00K

Operating Income

-$133.60M

EBITDA

-$129.50M

Operating Cash Flow

-$116.39M

Capital Expenditure

-$196.00K

Free Cash Flow

-$116.59M

Cash & ST Invst.

$311.30M

Total Debt

$679.00K

Jade Biosciences Performance Analysis

Jade Biosciences annual revenue and year-over-year revenue growth by fiscal year
Fiscal yearPeriod endRevenueYoY growth
20222022-12-31USD 0N/A
20232023-12-31USD 0N/A
20242024-12-31USD 0N/A
20252025-12-31USD 0N/A
Jade Biosciences sequential (quarter-over-quarter) revenue growth by fiscal quarter
Fiscal quarterPeriod endQoQ growth
Q22025-06-30N/A
Q32025-09-30N/A
Q42025-12-31N/A
Q12026-03-31N/A
Jade Biosciences annual diluted earnings per share and year-over-year EPS growth by fiscal year
Fiscal yearPeriod endDiluted EPSYoY growth
20222022-12-31USD -73.67123.5%
20232023-12-31USD -100.3836.3%
20242024-12-31USD -85.26-15.1%
20252025-12-31USD -4.06-95.2%
Jade Biosciences sequential (quarter-over-quarter) diluted earnings per share growth by fiscal quarter
Fiscal quarterPeriod endQoQ growth
Q22025-06-3062.8%
Q32025-09-3043.4%
Q42025-12-31-1.6%
Q12026-03-31-7.7%

Revenue Growth Rate

Annual and quarterly growth comparison

Currently no data to display.

Earnings Per Share Growth Rate

Annual and quarterly EPS growth comparison

Quarterly Performance

Name
Q1 2026YOY CHG

Revenue

$0.00

N/A

Gross Profit

-$9.00K

-125.0%

Gross Margin

0.00%

N/A

Market Cap

$1.22BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

N/A

Market Cap/Employee

$22.22M

N/A

Employees

55

N/A

Net Income

-$40.37M

-1503.2%

EBITDA

-$40.34M

-1504.7%

Quarterly Fundamentals

Name
Q1 2026YOY CHG

Total Cash

$311.30M

+308.5%

Total Debt

$679.00K

+117.6%

Accounts Receivable

$0.00

N/A

Inventory

$0.00

N/A

Long Term Debt

$679.00K

N/A

Short Term Debt

$0.00

-100.0%

Return on Assets

-40.57%

N/A

Return on Invested Capital

-44.96%

N/A

Free Cash Flow

-$24.08M

-118.0%

Operating Cash Flow

-$24.08M

-118.0%

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Questions About JBIO

What is the current price of Jade Biosciences?

Jade Biosciences is trading at $20.02 per share.

What is the 52-week range for Jade Biosciences?

Over the past 52 weeks, Jade Biosciences has traded between $6.67 and $28.00.

How much debt does Jade Biosciences have?

As of the most recent reporting period, Jade Biosciences reported total debt of $679.00K.

How much cash does Jade Biosciences have on hand?

Jade Biosciences reported $55.09M in cash and cash equivalents in its most recent financial results.

What is Jade Biosciences’s dividend yield?

Jade Biosciences does not currently have a dividend yield.

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