The following video is part of our "Motley Fool Conversations" series, in which, David Williamson, health-care editor and analyst, and Austin Smith, consumer-goods editor and analyst, discuss topics around the investing world.

In today's edition, David and Austin take a look at the worst health-care performers of 2012, focusing on the worst performer of the year, Dendreon. This video reflects back on the year that was but also takes a look at what Dendreon needs to do to be successful in 2012 and the threats on the company's horizon.

Looking for our prediction for 2012? Check out The Motley Fool's brand new report, "The Motley Fool's Top Stock for 2012." It highlights a company that is revolutionizing commerce in Latin America. You can get instant access to the name of this company by clicking here -- it's free.

This article represents the opinion of the writer, who may disagree with the “official” recommendation position of a Motley Fool premium advisory service. We’re motley! Questioning an investing thesis -- even one of our own -- helps us all think critically about investing and make decisions that help us become smarter, happier, and richer.