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Alector(NASDAQ) ALEC

Market Cap$303.71MMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.
Since IPO (2019)-85%
5 Year-90%
1 Year+5%
1 Month+80%
$2.73
+13.75%
+0.33Today
After hours$2.77+$0.04 (+1.47%)
Alector last closing stock price
MetricPriceDate
Last closeUSD 2.722026-09-02
Alector stock price return by period
PeriodPrice returnPrice at period startPeriod start date
1 week+10.57%USD 2.462026-08-26
1 month+80.13%USD 1.512026-08-03
3 month+50.28%USD 1.812026-06-04
Year to date+74.36%USD 1.562025-12-31
1 year+5.02%USD 2.592025-09-02
3 year-51.17%USD 5.572023-09-01
5 year-89.79%USD 26.642021-09-03
Since inception-84.89%USD 18.002019-02-07

Alector Financials at a Glance

Market Cap

$303.71MMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

Revenue (TTM)

$13.86M

Net Income (TTM)

-$117.85M

EPS (TTM)

-$1.09

P/E Ratio

-2.49

Dividend

$0.00

Beta (Volatility)

1.67 (High)

Price

$2.73

Volume

27.23

Open

$2.40

Previous Close

$2.72

Daily Range

$2.40 - $2.76

52-Week Range

$1.09 - $3.40

Estimated Earnings Date

Nov 5, 2026

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About Alector

Alector, Inc. makes medicines for brain diseases like Alzheimer's. Its treatments help the brain's immune system stop damage. These therapies reach the brain easier than standard drugs.

New Ways to Treat the Brain

  • AL137 Program: Antibody treatment designed to clear toxic plaques in the brain; targeted for patients with Alzheimer's disease.
  • ABC-Enabled siRNA: Technology platform used to block the production of harmful proteins in brain cells.
  • AL050 Program: Enzyme therapy in development for patients with genetic mutations linked to Parkinson's disease and Lewy body dementia.
  • Alector Brain Carrier: Specialized delivery tool that helps drugs reach targets inside the central nervous system.

Recent Strategic Shifts

  • Selected AL137 as the lead candidate for Alzheimer's disease treatment in 2026.
  • Ended the long-term research and development partnership with AbbVie in February 2025.
  • Received a termination notice for its global collaboration agreement with GSK in July 2026.
  • Discontinued the Phase 2 trial for the drug nivisnebart in April 2026 after poor results.
  • Reduced total staff numbers by approximately 47% in October 2025 to cut costs.

Crossing the Brain Barrier

Alector uses its platform to deliver medicines like enzymes directly into the brain. This approach aims to stop brain decay by fixing the body's own immune cells.

A Look at the Books

  • Collaboration revenue was $3.3 million for the three-month period ended June 30, 2026.
  • Net loss was $23.0 million for the three-month period ended June 30, 2026.
  • Research and development expenses were $19.5 million for the three-month period ended June 30, 2026.
  • Cash, cash equivalents, and marketable securities totaled $172.8 million as of June 30, 2026.
  • Accumulated deficit reached $1,018.0 million by the end of June 2026.

Evolution of the Business

Alector has shifted to new brain therapies after losing major partnerships and clinical trials. Future success depends on moving early drug candidates through human testing using its delivery platform.

AI Generated • Aug 7, 2026

Industry

Biotechnology

Employees

103

CEO

Arnon Rosenthal, PhD

Headquarters

South San Francisco, CA 94080, US

ALEC Financials

Key Financial Metrics (TTM)

Gross Margin

-360.92%

Operating Margin

-914.56%

Net Income Margin

-850.13%

Return on Equity

-531.04%

Return on Capital

-218.01%

Return on Assets

-58.10%

Earnings Yield

-40.16%

Dividend Yield

0.00%

Payout Ratio

0.00%

Stock Overview

Market Cap

$303.71MMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

Shares Outstanding

111.66M

Volume

27.23

Avg. Volume

995.99K

Financials (TTM)

Gross Profit

-$50.03M

Operating Income

-$126.79M

EBITDA

-$107.84M

Operating Cash Flow

-$158.23M

Capital Expenditure

-$160.00K

Free Cash Flow

-$158.39M

Cash & ST Invst.

$172.80M

Total Debt

$32.76M

Alector Performance Analysis

Alector annual revenue and year-over-year revenue growth by fiscal year
Fiscal yearPeriod endRevenueYoY growth
20222022-12-31USD 133,617,000-35.5%
20232023-12-31USD 97,062,000-27.4%
20242024-12-31USD 100,558,0003.6%
20252025-12-31USD 21,045,000-79.1%
Alector sequential (quarter-over-quarter) revenue growth by fiscal quarter
Fiscal quarterPeriod endQoQ growth
Q32025-09-30-58.6%
Q42025-12-3191.3%
Q12026-03-31-83.2%
Q22026-06-30217.4%
Alector annual diluted earnings per share and year-over-year EPS growth by fiscal year
Fiscal yearPeriod endDiluted EPSYoY growth
20222022-12-31USD -1.62257.8%
20232023-12-31USD -1.56-3.7%
20242024-12-31USD -1.23-20.9%
20252025-12-31USD -1.3912.6%
Alector sequential (quarter-over-quarter) diluted earnings per share growth by fiscal quarter
Fiscal quarterPeriod endQoQ growth
Q32025-09-30-13.3%
Q42025-12-31N/A
Q12026-03-3138.2%
Q22026-06-30N/A

Revenue Growth Rate

Annual and quarterly growth comparison

Earnings Per Share Growth Rate

Annual and quarterly EPS growth comparison

Quarterly Performance

Name
Q2 2026YOY CHG

Revenue

$3.32M

-57.8%

Gross Profit

$3.32M

+116.8%

Gross Margin

100.00%

N/A

Market Cap

$303.71MMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

N/A

Market Cap/Employee

$2.95M

N/A

Employees

103

N/A

Net Income

-$22.99M

+24.7%

EBITDA

-$18.73M

+31.4%

Quarterly Fundamentals

Name
Q2 2026YOY CHG

Total Cash

$172.80M

-43.8%

Total Debt

$32.76M

-17.0%

Accounts Receivable

$0.00

N/A

Inventory

$0.00

N/A

Long Term Debt

$13.70M

-55.2%

Short Term Debt

$19.06M

+114.0%

Return on Assets

-58.10%

N/A

Return on Invested Capital

-75.19%

N/A

Free Cash Flow

-$34.25M

+30.2%

Operating Cash Flow

-$34.22M

+30.2%

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Questions About ALEC

What is the current price of Alector?

Alector is trading at $2.72 per share.

What is the 52-week range for Alector?

Over the past 52 weeks, Alector has traded between $1.09 and $3.40.

How much debt does Alector have?

As of the most recent reporting period, Alector reported total debt of $32.76M.

How much cash does Alector have on hand?

Alector reported $59.92M in cash and cash equivalents in its most recent financial results.

What is Alector’s dividend yield?

Alector does not currently have a dividend yield.

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