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AnaptysBio(NASDAQ) ANAB

Current Price$55.02
Market Cap$1.63BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.
Since IPO (2017)+364%
5 Year+220%
1 Year+205%
1 Month-8%
AnaptysBio last closing stock price
MetricPriceDate
Last closeUSD 54.912026-07-23
AnaptysBio stock price return by period
PeriodPrice returnPrice at period startPeriod start date
1 week+1.4%USD 54.152026-07-16
1 month-7.61%USD 59.432026-06-23
3 month-6.74%USD 58.882026-04-24
Year to date+69.92%USD 32.322025-12-31
1 year+205.1%USD 18.002025-07-23
3 year+365.67%USD 11.792023-07-24
5 year+219.91%USD 17.162021-07-23
Since inception+364.27%USD 11.332017-01-26

AnaptysBio Financials at a Glance

Market Cap

$1.63BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

Revenue (TTM)

$232.39M

Net Income (TTM)

-$26.79M

EPS (TTM)

-$1.08

P/E Ratio

-50.83

Dividend

$0.00

Beta (Volatility)

0.87 (Low)

Price

$55.02

Volume

20,123

Open

$52.95

Previous Close

$55.02

Daily Range

$52.00 - $56.00

52-Week Range

$11.40 - $72.36

Estimated Earnings Date

Aug 5, 2026

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About AnaptysBio

AnaptysBio creates drugs for painful immune diseases. These treatments help patients with joint and skin issues. The company builds tools to stop harmful inflammation.

A Focused Drug Portfolio

  • Rosnilimab: Therapy for rheumatoid arthritis that removes specific T cells, which are immune cells that cause joint inflammation.
  • ANB033: Medicine for celiac disease, an immune reaction to gluten, that stops the body from attacking the gut.
  • ANB101: Drug designed to stop specific cells from releasing proteins that trigger autoimmune responses in the body.
  • Jemperli: Cancer medicine discovered by the company and sold by GSK to treat specific types of tumors.
  • Imsidolimab: Skin therapy licensed to Vanda Pharmaceuticals Inc. for treating rare and painful psoriasis flare-ups.

Strategic Steps Forward

  • Approved a plan in September 2025 to split into two independent, public companies to separate royalties from drug development.
  • Licensed imsidolimab to Vanda Pharmaceuticals Inc. in January 2025 for a $10 million upfront payment and future royalties.
  • Acquired global rights for the ANB101 program from Centessa Pharmaceuticals in November 2023.
  • Sold rights to future royalty payments to Sagard Healthcare Royalty Partners for $50 million in May 2024.

What Drives Success

AnaptysBio uses a specialized laboratory process to design antibodies that target specific biological triggers for disease. This precision allows the company to partner with global pharmaceutical giants while maintaining its own pipeline of experimental drugs.

Tracking the Numbers

  • Revenue reached $108.2 million in Q4 2025, a 151.1% increase from Q4 2024.
  • Net income hit $49.6 million in Q4 2025, up 327.8% from the previous year.
  • Operating cash flow grew to $98 million in Q4 2025, up 247% year-over-year.
  • Gross profit reached $216.2 million in Q4 2025, up 41166.6% from Q4 2024.
  • Market capitalization rose to $898.1 million in Q4 2025, up 234.1% from the previous year.

Evolution Summary

AnaptysBio has evolved from a discovery research firm into a clinical-stage developer with a focus on high-value immunology. Its strategy of licensing products to larger partners provides the capital needed to advance its internal drug candidates.

AI Generated • Apr 28, 2026

Industry

Biotechnology

Employees

104

CEO

Daniel R. Faga, MBA

Headquarters

San Diego, CA 92121-5801, US

ANAB Financials

Key Financial Metrics (TTM)

Gross Margin

116.42%

Operating Margin

17.56%

Net Income Margin

-11.53%

Return on Equity

442.91%

Return on Capital

93.32%

Return on Assets

-8.13%

Earnings Yield

-1.97%

Dividend Yield

0.00%

Payout Ratio

0.00%

Stock Overview

Market Cap

$1.63BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

Shares Outstanding

29.61M

Volume

20.12K

Avg. Volume

697.06K

Financials (TTM)

Gross Profit

$270.54M

Operating Income

$40.80M

EBITDA

$58.49M

Operating Cash Flow

$4.48M

Capital Expenditure

-$69.00K

Free Cash Flow

$4.41M

Cash & ST Invst.

$286.46M

Total Debt

$277.36M

AnaptysBio Performance Analysis

AnaptysBio annual revenue and year-over-year revenue growth by fiscal year
Fiscal yearPeriod endRevenueYoY growth
20222022-12-31USD 10,287,000-83.7%
20232023-12-31USD 17,157,00066.8%
20242024-12-31USD 91,280,000432.0%
20252025-12-31USD 234,603,000157.0%
AnaptysBio sequential (quarter-over-quarter) revenue growth by fiscal quarter
Fiscal quarterPeriod endQoQ growth
Q22025-06-30-19.8%
Q32025-09-30242.8%
Q42025-12-3141.8%
Q12026-03-31-76.4%
AnaptysBio annual diluted earnings per share and year-over-year EPS growth by fiscal year
Fiscal yearPeriod endDiluted EPSYoY growth
20222022-12-31USD -4.57116.9%
20232023-12-31USD -6.0833.0%
20242024-12-31USD -5.12-15.8%
20252025-12-31USD -0.46-91.0%
AnaptysBio sequential (quarter-over-quarter) diluted earnings per share growth by fiscal quarter
Fiscal quarterPeriod endQoQ growth
Q22025-06-30-4.7%
Q32025-09-30138.8%
Q42025-12-31203.8%
Q12026-03-31-216.5%

Revenue Growth Rate

Annual and quarterly growth comparison

Earnings Per Share Growth Rate

Annual and quarterly EPS growth comparison

Quarterly Performance

Name
Q1 2026YOY CHG

Revenue

$25.56M

-8.0%

Gross Profit

$24.95M

+286.0%

Gross Margin

97.61%

N/A

Market Cap

$1.63BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

N/A

Market Cap/Employee

$15.63M

N/A

Employees

104

N/A

Net Income

-$52.88M

-34.5%

EBITDA

-$31.38M

-52.2%

Quarterly Fundamentals

Name
Q1 2026YOY CHG

Total Cash

$286.46M

-15.7%

Total Debt

$277.36M

+1680.8%

Accounts Receivable

$25.75M

+44.0%

Inventory

$0.00

N/A

Long Term Debt

$275.24M

+1921.9%

Short Term Debt

$2.12M

+8.1%

Return on Assets

-8.13%

N/A

Return on Invested Capital

14.17%

N/A

Free Cash Flow

-$25.94M

-141.6%

Operating Cash Flow

-$25.92M

-142.2%

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Questions About ANAB

What is the current price of AnaptysBio?

AnaptysBio is trading at $55.02 per share.

What is the 52-week range for AnaptysBio?

Over the past 52 weeks, AnaptysBio has traded between $11.40 and $72.36.

How much debt does AnaptysBio have?

As of the most recent reporting period, AnaptysBio reported total debt of $277.36M.

How much cash does AnaptysBio have on hand?

AnaptysBio reported $248.47M in cash and cash equivalents in its most recent financial results.

What is AnaptysBio’s dividend yield?

AnaptysBio does not currently have a dividend yield.

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