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Vertex Pharmaceuticals(NASDAQ) VRTX

Market Cap$138.42BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.
Since IPO (1991)+12,036%
5 Year+181%
1 Year+34%
1 Month+7%
Premium Feature
Moneyball Superscore
90/100
$528.70
-3.19%
-17.42Today
After hours$530.00+$1.30 (+0.25%)
Vertex Pharmaceuticals last closing stock price
MetricPriceDate
Last closeUSD 528.902026-09-08
Vertex Pharmaceuticals stock price return by period
PeriodPrice returnPrice at period startPeriod start date
1 week-3.42%USD 547.652026-09-01
1 month+6.62%USD 496.072026-08-07
3 month+21.39%USD 435.712026-06-10
Year to date+16.66%USD 453.362025-12-31
1 year+33.81%USD 395.252025-09-08
3 year+54.18%USD 343.052023-09-08
5 year+181.2%USD 188.092021-09-09
Since inception+12,036%USD 4.501991-07-24

Vertex Pharmaceuticals Financials at a Glance

Market Cap

$138.42BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

Revenue (TTM)

$12.62B

Net Income (TTM)

$4.41B

EPS (TTM)

$17.19

P/E Ratio

31.77

Dividend

$0.00

Beta (Volatility)

0.57 (Low)

Price

$528.70

Volume

1,121,470.003

Open

$529.64

Previous Close

$528.90

Daily Range

$520.20 - $535.00

52-Week Range

$374.17 - $560.25

Estimated Earnings Date

Nov 2, 2026

VRTX News

Vertex Pharmaceuticals logo

Goldman Sachs Just Added Vertex Pharmaceuticals to Its Conviction List. Here's the Bull Case for the Big Biotech Stock

Prosper Junior BakinySep 8, 2026
Vertex Pharmaceuticals and Regeneron logos

Vertex vs. Regeneron: Which Biotech Giant Is the Better Buy Right Now?

Prosper Junior BakinySep 4, 2026
Vertex Pharmaceuticals and Visa logos

Inflation Is Rising Again. History Says These 2 Stocks Are Among the Smartest Places to Hide

Prosper Junior BakinyAug 24, 2026
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Vertex Pharmaceuticals: A Biotech Cash Cow With Pipeline Upside?

Motley Fool YouTubeAug 21, 2026
Vertex Pharmaceuticals logo

Vertex Pharmaceuticals' Rally Has a New Engine -- and Wall Street Thinks the Best Is Still Ahead

Prosper Junior BakinyAug 20, 2026
Doctor holding clipboard stands with virtual DNA double helix in the air near him.

7 Best Genomics Stocks for 2026 and How to Invest

Lyle DalyAug 17, 2026
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6 Best Healthcare Stocks for 2026 and How to Invest

Keith SpeightsAug 16, 2026
Vertex Pharmaceuticals logo

Vertex Pharmaceuticals Just Hit an All-Time High. Here's Why the Biotech Stock Could Soar Even More

Prosper Junior BakinyAug 14, 2026
Page 1

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About Vertex Pharmaceuticals

Vertex Pharmaceuticals Incorporated treats people with life-threatening genetic diseases. These medicines help patients manage cystic fibrosis and blood disorders. The company also develops new ways to treat severe pain.

Medicines for Rare Conditions

  • Cystic Fibrosis Treatments: Therapies like TRIKAFTA and ALYFTREK that treat genetic lung disease; generated $3.2 billion in the second quarter of 2026.
  • Genetic Blood Therapies: CASGEVY uses gene editing to treat sickle cell disease and beta thalassemia; recorded $76.4 million in the second quarter of 2026.
  • Acute Pain Management: JOURNAVX is an approved medicine for moderate-to-severe acute pain; produced $49.6 million in the second quarter of 2026.

Expanding Beyond Cystic Fibrosis

  • Agreed to acquire Crinetics Pharmaceuticals in July 2026 for approximately $10.0 billion to expand into endocrine disease treatments.
  • Acquired Alpine Immune Sciences and its lead molecule, povetacicept, for $5.0 billion in 2024 to target autoimmune diseases.
  • Partnered with Zai Lab and Ono Pharmaceuticals in 2025 to develop and sell povetacicept in Asian markets.
  • Secured reimbursement for ALYFTREK in four additional countries, including Spain, during the second quarter of 2026.

Specialized Science and Global Reach

Vertex operates a specialized global network to manufacture and distribute complex biological and cell therapies. The company maintains a high level of research investment to create first-in-class treatments for diseases with significant unmet needs.

Financial Performance in 2026

  • Total revenues rose to $3.3 billion in the second quarter of 2026, up 12% year over year.
  • Selling, general, and administrative expenses reached $582.2 million in the second quarter of 2026, up 37% year over year.
  • Cash, cash equivalents, and marketable securities totaled $13.6 billion as of June 30, 2026.
  • Market capitalization reached $126.1 billion in the second quarter of 2026, up 10.4% year over year.
  • Research and development expenses totaled $993.8 million in the second quarter of 2026, up 2% year over year.

A Changing Biotechnology Leader

Vertex has evolved from a cystic fibrosis specialist into a multi-disease biotechnology leader. Its expansion into gene editing and pain management diversification strengthens its long-term commercial profile.

AI Generated • Aug 5, 2026

Industry

Biotechnology

Sector

Health Care

Employees

6,400

CEO

Reshma Kewalramani, MD

Website

www.vrtx.com

Headquarters

Boston, MA 02210, US

VRTX Financials

Key Financial Metrics (TTM)

Gross Margin

86.04%

Operating Margin

38.59%

Net Income Margin

34.89%

Return on Equity

23.31%

Return on Capital

21.11%

Return on Assets

16.06%

Earnings Yield

3.15%

Dividend Yield

0.00%

Payout Ratio

0.00%

Stock Overview

Market Cap

$138.42BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

Shares Outstanding

253.46M

Volume

1.12M

Avg. Volume

1.48M

Financials (TTM)

Gross Profit

$10.86B

Operating Income

$4.87B

EBITDA

$5.44B

Operating Cash Flow

$4.29B

Capital Expenditure

-$496.80M

Free Cash Flow

$3.80B

Cash & ST Invst.

$7.85B

Total Debt

$1.98B

Vertex Pharmaceuticals Performance Analysis

Vertex Pharmaceuticals annual revenue and year-over-year revenue growth by fiscal year
Fiscal yearPeriod endRevenueYoY growth
20222022-12-31USD 8,748,200,00015.0%
20232023-12-31USD 9,839,000,00012.5%
20242024-12-31USD 10,984,400,00011.6%
20252025-12-31USD 12,074,600,0009.9%
Vertex Pharmaceuticals sequential (quarter-over-quarter) revenue growth by fiscal quarter
Fiscal quarterPeriod endQoQ growth
Q32025-09-303.8%
Q42025-12-314.9%
Q12026-03-31-7.4%
Q22026-06-3011.6%
Vertex Pharmaceuticals annual diluted earnings per share and year-over-year EPS growth by fiscal year
Fiscal yearPeriod endDiluted EPSYoY growth
20222022-12-31USD 12.8242.3%
20232023-12-31USD 13.898.4%
20242024-12-31USD -2.08N/A
20252025-12-31USD 15.32N/A
Vertex Pharmaceuticals sequential (quarter-over-quarter) diluted earnings per share growth by fiscal quarter
Fiscal quarterPeriod endQoQ growth
Q32025-09-305.3%
Q42025-12-3110.7%
Q12026-03-31-13.5%
Q22026-06-307.2%

Revenue Growth Rate

Annual and quarterly growth comparison

Earnings Per Share Growth Rate

Annual and quarterly EPS growth comparison

Quarterly Performance

Name
Q2 2026YOY CHG

Revenue

$3.33B

+12.5%

Gross Profit

$2.84B

+11.2%

Gross Margin

85.33%

N/A

Market Cap

$138.42BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

N/A

Market Cap/Employee

$21.63M

N/A

Employees

6,400

N/A

Net Income

$1.10B

+6.5%

EBITDA

$1.39B

+4.0%

Quarterly Fundamentals

Name
Q2 2026YOY CHG

Total Cash

$7.85B

+23.0%

Total Debt

$1.98B

+29.5%

Accounts Receivable

$2.13B

+12.7%

Inventory

$1.77B

+17.7%

Long Term Debt

$1.98B

+29.5%

Short Term Debt

$0.00

N/A

Return on Assets

16.06%

N/A

Return on Invested Capital

20.74%

N/A

Free Cash Flow

$1.01B

+9.3%

Operating Cash Flow

$1.13B

+4.9%

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Questions About VRTX

What is the current price of Vertex Pharmaceuticals?

Vertex Pharmaceuticals is trading at $528.90 per share.

What is the 52-week range for Vertex Pharmaceuticals?

Over the past 52 weeks, Vertex Pharmaceuticals has traded between $374.17 and $560.25.

How much debt does Vertex Pharmaceuticals have?

As of the most recent reporting period, Vertex Pharmaceuticals reported total debt of $1.98B.

How much cash does Vertex Pharmaceuticals have on hand?

Vertex Pharmaceuticals reported $6.15B in cash and cash equivalents in its most recent financial results.

What is Vertex Pharmaceuticals’s dividend yield?

Vertex Pharmaceuticals does not currently have a dividend yield.

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