Millennium Pharmaceuticals (NASDAQ:MLNM), the world's ninth-largest biotech company, is making a run for the No. 8 spot.

For the third quarter, Millennium saw revenue jump 51% year over year to $144.8 million, narrowing the company's loss to $92.3 million, or $0.31 per share. Driving the gain was Velcade, its blockbuster hopeful.

Approved in May, Velcade garnered $23.0 million in product sales during its first full quarter on the market, and has accounted for $30.9 million since its launch. As a treatment for multiple myeloma, Millennium now expects full-year sales to exceed $50 million, rather than the $25 million to $30 million it had previously forecast.

The company's revenue share from Integrilin, the heart drug Millennium co-promotes with Schering-Plough (NYSE:SGP), increased slightly to $47.9 million from $45.0 million. However, Millennium gained market share to 71%, reflecting its larger sales force.

In addition to product sales, the company received a $30 million milestone payment from its new partner for Velcade, Johnson & Johnson (NYSE:JNJ) subsidiary Ortho Biotech Products. Including the milestone payment for Velcade -- for which J&J owns marketing rights outside the U.S. -- strategic alliance revenue increased 46% to $73.9 million.

Jeff Hwang can be reached at JHwang@fool.com .