The S&P 500 edged down last week 0.42% to 1,104.49 after a mixed bag of economic data. Greece's woes also continued to keep gains in check. Despite a volatile month, though, the S&P closed February up 2.9%.

Pops and drops
Here are the five biggest S&P 500 upticks and five biggest S&P 500 drops of last week (measured Friday close to Friday close):

Winners on the week:

Company

Percentage Gain on the Week

Millipore (NYSE: MIL)

32.3%

Coca-Cola Enterprises (NYSE: CCE)

29.4%

JDS Uniphase

12.4%

Mylan Inc

11.9%

Office Depot (NYSE: ODP)

9.9%

Source: Capital IQ (a division of Standard & Poor's).

Losers on the week:

Company

Percentage Loss on the Week

H&R Block (NYSE: HRB)

(18.2%)

GameStop (NYSE: GME)

(10.9%)

Western Digital

(10.5%)

Monsanto (NYSE: MON)

(9.1%)

First Solar (Nasdaq: FSLR)

(8.8%)

Source: Capital IQ (a division of Standard & Poor's).

A closer look
Last week brought some welcome M&A activity. Shares of Millipore soared last week after the life sciences technology and tools company confirmed it was exploring "strategic alternatives," including a merger or outright sale. There was speculation that Thermo Fisher Scientific would acquire Millipore; however, over the weekend we learned that Merck has inked a deal to acquire Millipore for $7.2 billion (including assumed debt). The deal is said to diversify Merck's businesses and enhance its lab equipment unit.

In other M&A news, stock in Coca-Cola Enterprises soared last week after Coca-Cola agreed to buy its largest bottler's North American operations in a transaction valued at more than $13 billion. The remainder of the bottling operations, which exist in Europe, will operate independently and continue to produce and distribute Coke products in Europe. The move is a departure for Coke, which has long kept its bottling operations separate. As consumers drink fewer soft drinks, large-volume shipments from independent bottlers no longer make business sense. The move is seen as a way to give Coke greater flexibility to produce, bottle and ship the amount of inventory of a particular drink -- be it soda or niche drinks -- that the demand in the market dictates. The deal comes on the heels of archrival Pepsi's acquisition of its bottlers.

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Fool contributor Jennifer Schonberger does not own shares of any of the companies mentioned in this article. You can follow her on Twitter. Monsanto and Coca-Cola are Motley Fool Inside Value selections. First Solar is a Motley Fool Rule Breakers recommendation. Coca-Cola and PepsiCo are Motley Fool Income Investor recommendations. Motley Fool Options has recommended a diagonal call position on PepsiCo. The Motley Fool has a disclosure policy.