Biotechnology stocks are never short on volatility and today was no different as markets turned lower and biotech stocks were particularly hard hit.

The Nasdaq Biotechnology Index ETF (IBB 0.09%) dropped more than 2% as investors embraced safety and avoided risk. But while the 2% drop in the industry ETF was noteworthy, the move pales in comparison to the losses and gains posted by these three stocks.

Zogenix (ZGNX) and bluebird bio (BLUE) sunk by 12% and 8%, respectively.  And TherapeuticsMD (TXMD -3.42%) surged over 30% higher.

In the following slideshow, you'll learn what's behind the massive moves in these three stocks and see if I think any offer an investing angle worth considering.