Biotechnology stocks are never short on volatility and today was no different as markets turned lower and biotech stocks were particularly hard hit.

The Nasdaq Biotechnology Index ETF (NASDAQ:IBB) dropped more than 2% as investors embraced safety and avoided risk. But while the 2% drop in the industry ETF was noteworthy, the move pales in comparison to the losses and gains posted by these three stocks.

Zogenix (NASDAQ:ZGNX) and bluebird bio (NASDAQ:BLUE) sunk by 12% and 8%, respectively.  And TherapeuticsMD (NASDAQ:TXMD) surged over 30% higher.

In the following slideshow, you'll learn what's behind the massive moves in these three stocks and see if I think any offer an investing angle worth considering.