Please ensure Javascript is enabled for purposes of website accessibility

SPDR S&P Biotech ETF: A Closer Look

By Brian Feroldi - Sep 8, 2015 at 12:59PM

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More

Let's break down what this ETF offers investors.

Photo by Images_of_Money / Flickr Creative.

Biotech stocks are not for the faint of heart.

The majority of publicly traded biotechs are not yet profitable, which leads investors to value them by guessing about the future revenue potential of their pipeline based on how well drugs perform in clinical trails. Breaking news can lead to wild price swings, both good and bad, which scares away many investors from the sector. While I understand the trepidation, I think it's a mistake to simply ignore investing in biotech completely, as winning biotech stock returns can be extraordinary

So how can risk-averse investors add biotech exposure to their portfolio without having to take individual company risk? One easy way is to buy into an exchange-traded fund, or ETF, that owns a huge basket of biotech stocks. One such ETF that might be worthy of consideration is the SPDR S&P Biotech ETF (NYSEARCA:XBI).

Investors in this ETF have enjoyed a terrific long-term ride, as the returns since it first launched in 2006 have simply crushed the S&P 500. The annualized return since hitting the markets is currently a blistering 19.27%. 

XBI Chart

Of course, just because an ETF (or mutual fund, or stock) has performed well in the past doesn't necessarily mean it will perform as great going forward. To get a sense of what investors can expect from this ETF in the future, it's helpful to crack it open to how the fund operates. 

Currently, this fund holds 103 companies, which immediately offers investors great diversification. What's particularly interesting to me is that this fund uses an "equal-weight" strategy for sizing its investments. An equal-weight strategy simply means that all of the companies held in the fund are given the same initial weighting, regardless of the size of the company. Most other stock market indexes use a "weighted average market capitalization" system, in which more of the fund's money is invested in larger companies and less in smaller ones.

While I tend to like ETFs that use equal weighing, it's important for investors to understand that smaller-cap companies tend to be a bit more volatile, and that's especially true of biotech stocks, which means this ETF might be more prone to even more volatility than a weighted-average ETF would be. 

Quick stats:  
Category Specialty health
Expense ratio 0.35%
Yield 0.68%
Total assets $2.61 billion
Morningstar rating 4 stars
Price/prospective earnings 30
Turnover ratio 86%

Source: Morningstar.

A few numbers jump out at me. With an expense ratio of just 0.35%, this fund is a cheap way for investors to gain immediate diversification in the biotech sector. However, it also has a high turnover ratio of 86%, which means the fund is regularly adding and subtracting stocks, which can lead to higher taxes for shareholders -- though given the incredible performance of the fund, I doubt this has bothered most investors.

Another number to watch is that very high price-to-prospective earnings ratio of 30, which is far higher than the S&P 500's 19. However, seeing a high number shouldn't be all that surprising, especially since almost half of the companies the biotech fund holds don't even have a drug on the market yet, so profits could be a long ways away -- and this is just the nature of the industry.

Going small
This fund is concentrated in the smaller side of the biotech spectrum:

Market Capitalization 
Size% of Portfolio
Giant 3.19
Large 6.46
Medium 19.57
Small 36.01
Micro 34.76

Source: Morningstar 

The vast majority of assets are in the medium-, small- and micro-cap spectrum of biotech. So far, this strategy has produced some stellar returns, and the broad exposure of the fund should give some investors comfort, but the trend bears noting.

Given everything we've seen about this fund, I think it could make a find choice for investors seeking exposure to the crazy world of biotech but don't want to go about picking stocks for themselves. Just be sure you fully understand what you're buying.

Invest Smarter with The Motley Fool

Join Over 1 Million Premium Members Receiving…

  • New Stock Picks Each Month
  • Detailed Analysis of Companies
  • Model Portfolios
  • Live Streaming During Market Hours
  • And Much More
Get Started Now

Stocks Mentioned

SPDR Series Trust - SPDR S&P Biotech ETF Stock Quote
SPDR Series Trust - SPDR S&P Biotech ETF
$76.80 (-0.34%) $0.26

*Average returns of all recommendations since inception. Cost basis and return based on previous market day close.

Related Articles

Motley Fool Returns

Motley Fool Stock Advisor

Market-beating stocks from our award-winning analyst team.

Stock Advisor Returns
S&P 500 Returns

Calculated by average return of all stock recommendations since inception of the Stock Advisor service in February of 2002. Returns as of 06/27/2022.

Discounted offers are only available to new members. Stock Advisor list price is $199 per year.

Premium Investing Services

Invest better with The Motley Fool. Get stock recommendations, portfolio guidance, and more from The Motley Fool's premium services.