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| 1 Year | 5 Year | 5 Year Annualized | Since IPO | |
|---|---|---|---|---|
| CCCC | -61.26% | -91.32% | -38.64% | -91% |
| S&P | +12.65% | +91.73% | +13.89% | +101% |
C4 Therapeutics, Inc. engages in the development of targeted protein degradation science to develop a new generation of small molecule medicines used for treating diseases. It develops the Degronimid platform that incorporates small molecule binders to target disease-causing proteins and facilitate their destruction and clearance from the cell through the natural ubiquitin and proteasome system. The company was founded by James E. Bradner, Kenneth C. Anderson, Nathanael S. Gray and Marc A. Cohen in October 2015 and is headquartered in Watertown, MA.
| Q3 2025 | YOY Change | |
|---|---|---|
| Revenue | $11.23M | -26.9% |
| Gross Profit | $9.16M | -31.2% |
| Gross Margin | 81.55% | -5.1% |
| Market Cap | $158.00M | -60.0% |
| Market Cap / Employee | $1.44M | 0.0% |
| Employees | 110 | -24.1% |
| Net Income | -$32.17M | -30.4% |
| EBITDA | -$21.61M | 17.5% |
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| Q3 2025 | YOY Change | |
|---|---|---|
| Net Cash | $58.81M | -1.4% |
| Accounts Receivable | $6.54M | -36.7% |
| Inventory | 0 | 0.0% |
| Q3 2025 | YOY Change | |
|---|---|---|
| Long Term Debt | $55.25M | -10.1% |
| Short Term Debt | $6.22M | 10.4% |
| Q3 2025 | YOY Change | |
|---|---|---|
| Return On Assets | -37.12% | -7.4% |
| Return On Invested Capital | -31.34% | 49.7% |
| Q3 2025 | YOY Change | |
|---|---|---|
| Free Cash Flow | -$31.62M | -31.1% |
| Operating Free Cash Flow | -$31.21M | -29.3% |
| Metric | Q4 2024 | Q1 2025 | Q2 2025 | Q3 2025 | YoY Change |
|---|---|---|---|---|---|
| Price to Book | 1.05 | 0.52 | 0.52 | 0.91 | -45.36% |
| Price to Sales | 11.79 | 7.14 | 2.85 | 2.97 | -72.60% |
| Price to Tangible Book Value | 1.05 | 0.52 | 0.52 | 0.91 | -45.36% |
| Enterprise Value to EBITDA | -5.80 | -2.76 | 1.42 | 2.32 | -149.67% |
| Return on Equity | -45.6% | -45.6% | -53.0% | -60.0% | 30.39% |
| Total Debt | $65.76M | $64.37M | $62.92M | $61.46M | -8.39% |
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