NuCana Plc logo

NuCana Plc(NASDAQ) NCNA

Market Cap$5.60MMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.
Since IPO (2017)-100%
5 Year-100%
1 Year-71%
1 Month-16%
$1.36
+4.62%
+0.06Today
NuCana Plc last closing stock price
MetricPriceDate
Last closeUSD 1.302026-09-16
NuCana Plc stock price return by period
PeriodPrice returnPrice at period startPeriod start date
1 week-5.11%USD 1.372026-09-09
1 month-16.13%USD 1.552026-08-17
3 month-31.94%USD 1.912026-06-18
Year to date-63.89%USD 3.602025-12-31
1 year-70.59%USD 4.422025-09-16
3 year-99.96%USD 3,200.002023-09-15
5 year-99.99%USD 11,800.002021-09-17
Since inception-100%USD 80,750.002017-09-28

NuCana Plc Financials at a Glance

Market Cap

$5.60MMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

Revenue (TTM)

£0.00

Net Income (TTM)

-£9.73M

EPS (TTM)

-$3.22

P/E Ratio

-0.40

Dividend

$0.00

Beta (Volatility)

1.10 (Average)

Price

$1.36

Volume

44,323.855

Open

$1.33

Previous Close

$1.30

Daily Range

$1.30 - $1.37

52-Week Range

$1.21 - $7.22

Estimated Earnings Date

Nov 12, 2026

NCNA News

No articles available.

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About NuCana Plc

NuCana plc is a clinical-stage biopharmaceutical firm focused on developing advanced therapies for oncology. The company leverages its proprietary ProTide technology platform to create innovative drug candidates aimed at treating various types of cancer.

Products and Services
  • Acelarin: Targeting advanced solid tumors and various cancers
  • NUC-3373: A ProTide derivative of 5-fluorouracil for advanced colorectal cancer
  • NUC-7738: A nucleoside analog for advanced solid and hematological malignancies
Growth Outlook
  • Multiple ongoing clinical trials for Acelarin across various cancer types
  • NUC-3373 shows promise in early-stage trials for colorectal cancer
  • Strong partnerships with Cardiff University enhance research capabilities
Financial Highlights
  • Cash and cash equivalents of approximately $19.39 million as of June 30, 2026
  • Operating expenses totaled $3.48 million in Q2 2026
  • Net income of -$3.10 million reported for Q2 2026
NuCana plc is positioned in the biotechnology sector, focusing on innovative cancer therapies. The company's ProTide technology platform is central to its drug development efforts, with several candidates in various stages of clinical trials. Acelarin, one of the key products, is undergoing multiple evaluations, indicating a robust pipeline that could lead to significant advancements in cancer treatment. The financial data reflects a strong cash position, which is crucial for funding ongoing research and development activities. Despite reporting net losses, the company maintains a solid cash reserve, allowing it to continue its operations and clinical trials. The strategic collaborations with academic institutions further bolster its research capabilities, potentially leading to breakthroughs in oncology.
AI Generated • Aug 31, 2026

Industry

Biotechnology

Employees

12

CEO

Hugh Stephen Griffith, MBA

Headquarters

Edinburgh, MD EH12 9DT, GB

NCNA Financials

Key Financial Metrics (TTM)

Gross Margin

0.00%

Operating Margin

0.00%

Net Income Margin

0.00%

Return on Equity

-41.95%

Return on Capital

-80.43%

Return on Assets

-37.96%

Earnings Yield

-2.50%

Dividend Yield

0.00%

Payout Ratio

0.00%

Stock Overview

Market Cap

$5.60MMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

Shares Outstanding

4.31M

Volume

44.32K

Avg. Volume

61.94K

Financials (TTM)

Gross Profit

-£71.37K

Operating Income

-£13.30M

EBITDA

-£14.37M

Operating Cash Flow

-£4.98M

Capital Expenditure

-£174.00K

Free Cash Flow

-£5.15M

Cash & ST Invst.

£19.39M

Total Debt

£667.94K

NuCana Plc Performance Analysis

NuCana Plc annual revenue and year-over-year revenue growth by fiscal year
Fiscal yearPeriod endRevenueYoY growth
20222022-12-31GBP 0N/A
20232023-12-31GBP 0N/A
20242024-12-31GBP 0N/A
20252025-12-31GBP 0N/A
NuCana Plc sequential (quarter-over-quarter) revenue growth by fiscal quarter
Fiscal quarterPeriod endQoQ growth
Q32025-09-30N/A
Q42025-12-31N/A
Q12026-03-31N/A
Q22026-06-30N/A
NuCana Plc annual diluted earnings per share and year-over-year EPS growth by fiscal year
Fiscal yearPeriod endDiluted EPSYoY growth
20222022-12-31GBP -3,775.53-29.5%
20232023-12-31GBP -3,266.68-13.5%
20242024-12-31GBP -1,635.98-49.9%
20252025-12-31GBP -17.20-98.9%
NuCana Plc sequential (quarter-over-quarter) diluted earnings per share growth by fiscal quarter
Fiscal quarterPeriod endQoQ growth
Q32025-09-3099.6%
Q42025-12-31-515.4%
Q12026-03-31-60.0%
Q22026-06-3040.8%

Revenue Growth Rate

Annual and quarterly growth comparison

Currently no data to display.

Earnings Per Share Growth Rate

Annual and quarterly EPS growth comparison

Quarterly Performance

Name
Q2 2026YOY CHG

Revenue

£0.00

N/A

Gross Profit

-£71.37K

N/A

Gross Margin

0.00%

N/A

Market Cap

$5.60MMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

N/A

Market Cap/Employee

$509.31K

N/A

Employees

11

N/A

Net Income

-£3.10M

+87.2%

EBITDA

-£3.38M

+70.7%

Quarterly Fundamentals

Name
Q2 2026YOY CHG

Total Cash

£19.39M

+129.6%

Total Debt

£667.94K

+333.7%

Accounts Receivable

£2.48M

-53.0%

Inventory

£0.00

N/A

Long Term Debt

£633.16K

+701.5%

Short Term Debt

£35.00K

-53.3%

Return on Assets

-37.96%

N/A

Return on Invested Capital

-63.87%

N/A

Free Cash Flow

-£1.93M

+57.6%

Operating Cash Flow

-£1.93M

+57.1%

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Questions About NCNA

What is the current price of NuCana Plc?

NuCana Plc is trading at $1.36 per share.

What is the 52-week range for NuCana Plc?

Over the past 52 weeks, NuCana Plc has traded between $1.21 and $7.22.

How much debt does NuCana Plc have?

As of the most recent reporting period, NuCana Plc reported total debt of £891.91K.

How much cash does NuCana Plc have on hand?

NuCana Plc reported £25.89M in cash and cash equivalents in its most recent financial results.

What is NuCana Plc’s dividend yield?

NuCana Plc does not currently have a dividend yield.

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