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Prime Medicine(NASDAQ) PRME

Market Cap$527.40MMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.
Since IPO (2022)-81%
5 YearN/A
1 Year-30%
1 Month-27%
$2.81
-3.94%
-0.11Today
After hours$2.86+$0.06 (+1.96%)
Prime Medicine last closing stock price
MetricPriceDate
Last closeUSD 2.812026-08-03
Prime Medicine stock price return by period
PeriodPrice returnPrice at period startPeriod start date
1 week-6.64%USD 3.012026-07-27
1 month-27.39%USD 3.872026-07-02
3 month-17.11%USD 3.392026-05-05
Year to date-19.02%USD 3.472025-12-31
1 year-30.45%USD 4.042025-08-01
3 year-79.55%USD 13.742023-08-04
Since inception-81%USD 15.372022-10-20

Prime Medicine Financials at a Glance

Market Cap

$527.40MMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

Revenue (TTM)

$4.03M

Net Income (TTM)

-$198.37M

EPS (TTM)

-$1.25

P/E Ratio

-2.33

Dividend

$0.00

Beta (Volatility)

1.96 (High)

Price

$2.81

Volume

3,953,389.615

Open

$2.91

Previous Close

$2.81

Daily Range

$2.72 - $2.91

52-Week Range

$2.67 - $6.94

Estimated Earnings Date

Aug 6, 2026

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About Prime Medicine

Prime Medicine, Inc. is a biotechnology company dedicated to advancing precision genetic medicine through its Prime Editing technology. This transformative platform enables precise, efficient, and versatile gene editing, offering the potential to treat a wide range of genetic diseases. Underpinned by a strong portfolio of investigational programs, the company's aim is to deliver one-time curative therapies. Founded by leading experts in gene editing, Prime Medicine is strategically positioned for long-term growth through innovative therapies, strategic partnerships, and a robust intellectual property portfolio.

Products and Services

Prime Editing technology platform for precise and efficient gene editing.

Development pipelines focused on hematology, liver, lung, ocular, and neuromuscular therapies.

Prime Assisted Site-Specific Integrase Gene Editing (PASSIGE) for precise genome modifications.

Collaborations with research institutions and industry leaders for prime application expansion.

What Makes Prime Medicine, Inc. Special

Prime Medicine, Inc. stands out due to its Prime Editing technology, which uniquely allows for precise DNA editing without causing double-stranded breaks. This capability reduces unwanted genetic alterations, thus offering potentially safer and more effective treatments compared to traditional gene-editing technologies.

Five Things You Need to Know

Prime Editing technology can potentially address 90% of disease-causing genetic mutations.

Prime Medicine's pipeline spans diverse therapeutic areas, including rare genetic disorders and common chronic diseases.

The company's leadership team includes pioneers in the gene-editing field and seasoned biotech executives.

Robust intellectual property portfolio, with exclusive licenses from renowned research institutions.

Focus on forming significant partnerships to accelerate the development and commercialization of genetic therapies.

AI Generated • Apr 16, 2026

Industry

Biotechnology

Employees

146

CEO

Allan Jacob Reine, MD

Headquarters

Cambridge, MA 02139, US

PRME Financials

Key Financial Metrics (TTM)

Gross Margin

-1082.70%

Operating Margin

-5121.76%

Net Income Margin

-4917.55%

Return on Equity

-188.82%

Return on Capital

-87.80%

Return on Assets

-67.31%

Earnings Yield

-42.92%

Dividend Yield

0.00%

Payout Ratio

0.00%

Stock Overview

Market Cap

$527.40MMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

Shares Outstanding

180.62M

Volume

3.95M

Avg. Volume

3.30M

Financials (TTM)

Gross Profit

-$43.68M

Operating Income

-$206.61M

EBITDA

-$190.90M

Operating Cash Flow

-$156.42M

Capital Expenditure

-$2.32M

Free Cash Flow

-$158.74M

Cash & ST Invst.

$135.50M

Total Debt

$114.51M

Prime Medicine Performance Analysis

Prime Medicine annual revenue and year-over-year revenue growth by fiscal year
Fiscal yearPeriod endRevenueYoY growth
20222022-12-31USD 0N/A
20232023-12-31USD 0N/A
20242024-12-31USD 2,983,000N/A
20252025-12-31USD 4,632,00055.3%
Prime Medicine sequential (quarter-over-quarter) revenue growth by fiscal quarter
Fiscal quarterPeriod endQoQ growth
Q22025-06-30-23.3%
Q32025-09-309.9%
Q42025-12-31-31.6%
Q12026-03-312.1%
Prime Medicine annual diluted earnings per share and year-over-year EPS growth by fiscal year
Fiscal yearPeriod endDiluted EPSYoY growth
20222022-12-31USD -1.46-24.0%
20232023-12-31USD -2.1849.1%
20242024-12-31USD -1.65-24.2%
20252025-12-31USD -1.35-18.1%
Prime Medicine sequential (quarter-over-quarter) diluted earnings per share growth by fiscal quarter
Fiscal quarterPeriod endQoQ growth
Q22025-06-30-2.7%
Q32025-09-3021.4%
Q42025-12-3118.8%
Q12026-03-31-7.7%

Revenue Growth Rate

Annual and quarterly growth comparison

Earnings Per Share Growth Rate

Annual and quarterly EPS growth comparison

Quarterly Performance

Name
Q1 2026YOY CHG

Revenue

$856.00K

-41.1%

Gross Profit

-$1.00M

-168.8%

Gross Margin

-1.17%

N/A

Market Cap

$527.40MMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

N/A

Market Cap/Employee

$3.61M

N/A

Employees

146

N/A

Net Income

-$49.12M

+5.3%

EBITDA

-$47.27M

+5.8%

Quarterly Fundamentals

Name
Q1 2026YOY CHG

Total Cash

$135.50M

-6.1%

Total Debt

$114.51M

-5.5%

Accounts Receivable

$0.00

-100.0%

Inventory

$0.00

N/A

Long Term Debt

$105.97M

-7.3%

Short Term Debt

$8.55M

+24.6%

Return on Assets

-67.31%

N/A

Return on Invested Capital

-79.95%

N/A

Free Cash Flow

-$42.92M

+16.3%

Operating Cash Flow

-$42.71M

+12.6%

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Questions About PRME

What is the current price of Prime Medicine?

Prime Medicine is trading at $2.81 per share.

What is the 52-week range for Prime Medicine?

Over the past 52 weeks, Prime Medicine has traded between $2.67 and $6.94.

How much debt does Prime Medicine have?

As of the most recent reporting period, Prime Medicine reported total debt of $114.51M.

How much cash does Prime Medicine have on hand?

Prime Medicine reported $64.11M in cash and cash equivalents in its most recent financial results.

What is Prime Medicine’s dividend yield?

Prime Medicine does not currently have a dividend yield.

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