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| 1 Year | 5 Year | 5 Year Annualized | Since IPO | |
|---|---|---|---|---|
| PTGX | +63.34% | +293.84% | +31.54% | +556% |
| S&P | +14.84% | +96.04% | +14.41% | +208% |
Protagonist Therapeutics, Inc. a clinical-stage biopharmaceutical company, which engages in discovering and developing peptide-based therapeutic drugs to address unmet medical needs. Its product pipeline includes PTG-300, PTG-200, and PN-943. The company was founded by Mark L. Smythe on August 22, 2006 and is headquartered in Newark, CA.
The company could soon be swallowed by a very large peer -- which also happens to be a business partner.
| Q2 2025 | YOY Change | |
|---|---|---|
| Revenue | $5.55M | 33.1% |
| Gross Profit | $5.24M | 60.1% |
| Gross Margin | 94.52% | 15.9% |
| Market Cap | $3.43B | 68.6% |
| Market Cap / Employee | $26.35M | 45.2% |
| Employees | 130 | 4.0% |
| Net Income | -$34.77M | -13.6% |
| EBITDA | -$41.74M | -10.1% |
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| Q2 2025 | YOY Change | |
|---|---|---|
| Net Cash | $168.54M | -52.6% |
| Accounts Receivable | $23.36M | 54232.6% |
| Inventory | 0 | 0.0% |
| Q2 2025 | YOY Change | |
|---|---|---|
| Long Term Debt | $9.11M | -17.0% |
| Short Term Debt | $2.17M | 0.0% |
| Q2 2025 | YOY Change | |
|---|---|---|
| Return On Assets | 7.81% | -28.5% |
| Return On Invested Capital | -21.34% | 24.2% |
| Q2 2025 | YOY Change | |
|---|---|---|
| Free Cash Flow | -$29.59M | -111.0% |
| Operating Free Cash Flow | -$28.78M | -110.7% |
| Metric | Q3 2024 | Q4 2024 | Q1 2025 | Q2 2025 | YoY Change |
|---|---|---|---|---|---|
| Price to Earnings | 16.88 | 9.18 | 63.57 | 77.56 | 488.03% |
| Price to Book | 4.88 | 4.32 | 4.37 | 4.97 | 37.10% |
| Price to Sales | 8.58 | 5.90 | 14.65 | 16.78 | 152.10% |
| Price to Tangible Book Value | 4.88 | 4.32 | 4.37 | 4.97 | 37.10% |
| Price to Free Cash Flow TTM | 12.13 | 14.02 | 9.08 | 94.62 | 928.25% |
| Enterprise Value to EBITDA | -56.90 | 16.92 | -130.14 | -70.71 | 70.56% |
| Free Cash Flow Yield | 8.2% | 7.1% | 11.0% | 1.1% | -90.27% |
| Return on Equity | 41.0% | 54.4% | 9.0% | 8.6% | -78.85% |
| Total Debt | $10.90M | $10.87M | $11.36M | $11.28M | 2.81% |
PTGX earnings call for the period ending March 31, 2020.
PTGX earnings call for the period ending March 31, 2019.
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