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| 1 Year | 5 Year | 5 Year Annualized | Since IPO | |
|---|---|---|---|---|
| PTGX | +84% | +277.25% | +30.41% | +611% |
| S&P | +14.08% | +93.57% | +14.12% | +213% |
Protagonist Therapeutics, Inc. a clinical-stage biopharmaceutical company, which engages in discovering and developing peptide-based therapeutic drugs to address unmet medical needs. Its product pipeline includes PTG-300, PTG-200, and PN-943. The company was founded by Mark L. Smythe on August 22, 2006 and is headquartered in Newark, CA.
The company could soon be swallowed by a very large peer -- which also happens to be a business partner.
| Q3 2025 | YOY Change | |
|---|---|---|
| Revenue | $4.71M | 0.8% |
| Gross Profit | $4.35M | 8.0% |
| Gross Margin | 92.34% | 6.2% |
| Market Cap | $4.13B | 55.9% |
| Market Cap / Employee | $32.29M | 52.3% |
| Employees | 128 | 0.0% |
| Net Income | -$39.34M | -18.5% |
| EBITDA | -$46.06M | -12.9% |
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| Q3 2025 | YOY Change | |
|---|---|---|
| Net Cash | $113.71M | -13.3% |
| Accounts Receivable | $0.58M | 0.0% |
| Inventory | 0 | 0.0% |
| Q3 2025 | YOY Change | |
|---|---|---|
| Long Term Debt | $8.52M | -21.5% |
| Short Term Debt | $2.23M | 4851.1% |
| Q3 2025 | YOY Change | |
|---|---|---|
| Return On Assets | 7.03% | -29.6% |
| Return On Invested Capital | -21.34% | 24.2% |
| Q3 2025 | YOY Change | |
|---|---|---|
| Free Cash Flow | -$2.03M | 92.9% |
| Operating Free Cash Flow | -$1.94M | 93.0% |
| Metric | Q4 2024 | Q1 2025 | Q2 2025 | Q3 2025 | YoY Change |
|---|---|---|---|---|---|
| Price to Earnings | 9.18 | 63.57 | 77.56 | 104.88 | 521.25% |
| Price to Book | 4.32 | 4.37 | 4.97 | 6.18 | 26.43% |
| Price to Sales | 5.90 | 14.65 | 16.78 | 20.25 | 135.88% |
| Price to Tangible Book Value | 4.32 | 4.37 | 4.97 | 6.18 | 26.43% |
| Price to Free Cash Flow TTM | 14.02 | 9.08 | 94.62 | 66.49 | 448.36% |
| Enterprise Value to EBITDA | 16.92 | -130.14 | -70.71 | -79.70 | 40.08% |
| Free Cash Flow Yield | 7.1% | 11.0% | 1.1% | 1.5% | -81.76% |
| Return on Equity | 54.4% | 9.0% | 8.6% | 7.8% | -80.96% |
| Total Debt | $10.87M | $11.36M | $11.28M | $10.75M | -1.39% |
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PTGX earnings call for the period ending March 31, 2020.
PTGX earnings call for the period ending March 31, 2019.
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